Skip to main content
SpringerLink
Log in
Book cover

Encyclopedia of Pathology pp 1–3Cite as

Lymphangioma, Soft Tissue

  • Living reference work entry
  • First Online:

  • 45 Accesses

Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

Cystic hygroma; Lymphatic malformation

Definition

Lymphangiomas are benign malformations of the lymphatic system with channels and cystic spaces of varying size that may occur throughout the body. They are categorized into microcystic type (cavernous lymphangioma), macrocystic type (cystic hygroma), or mixed type.

Clinical Features

  • Incidence

    Lymphangiomas represent 4% of all vascular tumors and 25% of all benign pediatric vascular tumors, with an incidence of approximately 1 in 2000–4000 live births in congenital cases (Miceli and Stewart, 2019; Sun et al., 2017).

  • Age

    Lymphangiomas typically present at birth or in the first few years of life. They are often diagnosed prenatally (Goldblum et al., 2013).

  • Sex

    There is no gender bias in terms of their occurrence (Goldblum et al., 2013).

  • Site

    The most common sites are the head and neck (48%). Other reported sites are the trunk and extremities (42%). Some cases arise at the intrathoracic or abdominal compartment (10%) (Sun et al., 2017...

This is a preview of subscription content, log in via an institution.

References

  • Beham, A. (2013). Lymphangioma. In Fletcher, C. D. M., Bridge, J. A., Hogendoorn, P. C. W., & Mertens, F. (Ed.), WHO Classification of Tumors of Soft Tissue & Bone (4th ed., pp. 144–145)

    Google Scholar 

  • Goldblum, J. R., Folpe, A. L., & Weiss, S. W. (2013). Tumors and malformations of lymphatic vessels. In F. M. Enzinger & S. W. Weiss (Eds.), Enzinger and Weiss’s soft tissue tumors (6th ed., pp. 733–748). Philadelphia: Mosby Elsevier.

    Google Scholar 

  • Miceli, A., & Stewart, K. M. (2019). Lymphangioma. StatPearls [Internet]. Treasure Island: StatPearls Publishing. https://www.ncbi.nlm.nih.gov/pubmed/?term=lymphangioma+statpearls. Accessed 10 July 2019.

  • Sun, R. W., Tuchin, V. V., Zharov, V. P., Galanzha, E. I., & Richter, G. T. (2017). Current status, pitfalls and future directions in the diagnosis and therapy of lymphatic malformation. Journal of Biophotonics, 11, e201700124.

    Article  Google Scholar 

  • Suthiwartnarueput, W., Kiatipunsodsai, S., Kwankua, A., & Chaumrattanakul, U. (2012). Lymphangioma of the small bowel mesentery: A case report and review of the literature. World Journal of Gastroenterology, 18(43), 6328–6332.

    Article  Google Scholar 

  • Wu, J. K., Kitajewski, C., Reiley, M., Keung, C. H., Monteagudo, J., Andrew, J. P., Liou, P., Thirumoorthi, A., Wong, A., & Kandel, J. J. (2015). Aberrant lymphatic endothelial progenitors in lymphatic malformation development. PLoS One, 10(2), e0117352. https://doi.org/10.1371/journal.pone.0117352.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology, Hamanomachi Hospital, Fukuoka, Japan

    Chie Abe

  2. Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

    Taro Mori, Yuichi Yamada & Yoshinao Oda

Authors
  1. Chie Abe
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Taro Mori
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yuichi Yamada
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Yoshinao Oda
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yoshinao Oda .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Abe, C., Mori, T., Yamada, Y., Oda, Y. (2020). Lymphangioma, Soft Tissue. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5487-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-28845-1_5487-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation