Synonyms
Definition
A condition of benign proliferation of adipose tissue within renal sinus, hilum, and perirenal space, replacing the renal parenchyma. Renal replacement lipomatosis is characterized by complete replacement of the kidney by adipose tissue, with varying degrees of fibrosis (Ratkal et al. 2015).
Clinical Features
Incidence
Rare.
Age
Any age.
Sex
Both male and female.
Site
Renal sinus, hilum, and perirenal space.
Treatment
None.
Outcome
Benign.
Macroscopy
The kidney is usually enlarged and presents with a gross fibro-fatty appearance and renal cortical atrophy. It is usually associated with chronic pyelonephritis, renal lithiasis, and hydronephrosis. The shape of the kidney is always preserved (Rha et al. 2004).
Microscopy
The renal cortex is extremely atrophied, with varying degrees of hydronephrosis or pyonephrosis as well as acute and chronic pyelonephritic changes. There is marked proliferation of adipose tissue in the renal sinus, with...
References and Further Reading
Ratkal, V., Chawla, A., Mishra, D. K., & Krishna, S. (2015). Renal replacement lipomatosis of the right kidney. BML Case Reports, 6, 2015.
Rha, S. E., Byun, J. Y., Jung, S. E., Oh, S. N., Choi, Y. J., Lee, A., & Lee, J. M. (2004). The renal sinus: Pathologic spectrum and multimodality imaging approach. Radiographics, 24(Suppl 1), S117–S131.
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Cimadamore, A., Montironi, R. (2019). Renal Sinus Lipomatosis. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4927-1
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DOI: https://doi.org/10.1007/978-3-319-28845-1_4927-1
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