Benign Fibrous Histiocytoma

Synonyms

Dermatofibroma; Sclerosing hemangioma

Definition

Benign fibrous histiocytoma is a cutaneous tumor with predominantly dermal involvement, mainly composed of cells with fibro-histiocytic differentiation.

Clinical Features

• Incidence

  In general, BFH is a very common neoplasm, but involvement of the scrotum and the penis is exceedingly rare (Dehner and Smith 1970; Kinoshita et al. 1985; Huan et al. 2003).

• Age

  It may occur at any age, but it is most common in adults.

• Treatment

  The treatment of choice is surgical excision.

• Outcome

  Complete surgical excision is usually curative.

Macroscopy

BFH appears as a firm, non-encapsulated lesion of the dermis, with white to yellow cut surface. Cystic changes and hemorrhage may be present.

Microscopy

Histologically, there is a dermal-centered proliferation of bland spindle fibroblast-like cells and of histiocytoid cells, entrapping thick collagen fibers, especially at the periphery of the tumor (Fig. 1). The overlying epidermis is hyperplastic...