Synonyms
Formerly called Cylindroma
Definition
Adenoid cystic carcinoma is a basaloid tumor composed of epithelial and myoepithelial cells arranged in variable morphologic configurations, including tubular, cribriform, and solid patterns (El-Naggar and Huvos 2005). Adenoid cystic carcinoma manifests as a slowly growing mass often accompanied by pain and, in some cases, by facial paralysis (Rousseau and Badoual 2010). It is a locally aggressive tumor having relentless clinical course and usually a fatal outcome (El-Naggar and Huvos 2005).
Adenoid cystic carcinoma tubular pattern (HEX20)
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References and Further Reading
El-Naggar, A. K., & Huvos, A. G. (2005). Adenoid cystic carcinoma. In L. Barnes, J. W. Eveson, P. Reichart, & D. Sidransky (Eds.), World Health Organization classification of tumours. Pathology and genetics of head and neck tumours (pp. 221–222). Lyon: IARC Press.
Ellis, G. L., & Corio, R. L. (1983). Acinic cell adenocarcinoma. A clinicopathologic analysis of 294 cases. Cancer, 52, 542–549.
Ellis, G. L., & Auclair, P. L. (2008). Tumors of the salivary glands. Atlas of Tumor Pathology Fourth Series Fascicle 9. Washington, DC: Armed Forces Institute of Pathology.
Just, P. A., Miranda, L., Elouaret, Y., Meatchi, T., Hans, S., & Badoual, C. (2008). Classification of salivary gland tumors. Annales Otolaryngol Chirurgie Cervicofaciale, 125(6), 331–340.
Rousseau, A., & Badoual, C. (2010). Head and neck: Salivary gland tumors: an overview. Atlas Genet Cytogenet Oncol Haematol. URL: http://AtlasGeneticsOncology.org/Tumors/SalivGlandOverviewID5328.html.
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El Naderi, S., Badoual, C. (2016). Adenoid Cystic Carcinoma, Salivary Glands of. In: Volavšek, M. (eds) Head and Neck Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28618-1_1831
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DOI: https://doi.org/10.1007/978-3-319-28618-1_1831
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