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Measuring the Skin pp 1–6Cite as

Assessing Cutaneous Sensory Function and Vasomotor Responses

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Abstract

Cutaneous sensory function can be assessed under different conditions such as physiological, pathological and following certain treatments. Quantitative sensory testing (QST) includes a battery of stimulus modalities and response evaluation methods. Application of QST assists in understanding of potential mechanisms involved in sensory transduction, transmission, and perception under normal and pathophysiological conditions. QST has been utilized in mechanism-based diagnosis, prevention, and management of skin related disorders. In line, vasomotor responses can also be monitored in a real-time and dynamic manner. Skin vasomotor reactions such as cutaneous vasodilatation and vasoconstriction are under control of several systems including endothelial and adrenergic systems and malfunctioning would generally result in different skin circulation disorders. Cutaneous drug delivery would consequently be affected by those alterations. This chapter presents examples of assessing cutaneous sensory function and vasomotor responses in human skin and how body region or sex could influence the skin responsiveness.

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Authors and Affiliations

  1. Department of Health Science and Technology, Faculty of Medicine, Center for Sensory-Motor Interaction (SMI), Aalborg University, Fredrik Bajers Vej 7D3, 9220, Aalborg, Denmark

    Parisa Gazerani, Thomas A. Nielsen & Lars Arendt-Nielsen

Authors
  1. Parisa Gazerani
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  2. Thomas A. Nielsen
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  3. Lars Arendt-Nielsen
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Corresponding author

Correspondence to Parisa Gazerani .

Editor information

Editors and Affiliations

  1. Medecine Vasculaire Lab. Ingénierie et de Biologie Cutanées, CHU Besancon Service Dermatologie et, Besancon, France

    Philippe Humbert

  2. San Francisco, California, USA

    Howard Maibach

  3. Department of Dermatology, Saint Jacques University Hospital, Besançon, France

    Ferial Fanian

  4. Univ. Besançon Dépt. Dermatologie, Besançon, France

    Pierre Agache

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© 2015 Springer International Publishing Switzerland

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Gazerani, P., Nielsen, T., Arendt-Nielsen, L. (2015). Assessing Cutaneous Sensory Function and Vasomotor Responses. In: Humbert, P., Maibach, H., Fanian, F., Agache, P. (eds) Measuring the Skin. Springer, Cham. https://doi.org/10.1007/978-3-319-26594-0_61-1

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  • DOI: https://doi.org/10.1007/978-3-319-26594-0_61-1

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  • Publisher Name: Springer, Cham

  • Online ISBN: 978-3-319-26594-0

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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