Glucosinolates: Novel Sources and Biological Potential

  • Ivica BlaževićEmail author
  • Sabine Montaut
  • Franko Burčul
  • Patrick Rollin
Reference work entry
Part of the Reference Series in Phytochemistry book series (RSP)


In this chapter, some of the most recent information on glucosinolate-containing plant families is presented. Glucosinolates (GLs) are structurally homogenous secondary metabolites present in the Brassicaceae, Capparidaceae, Moringaceae, and Resedaceae families, as well as in other less-studied families of the order Brassicales. Based on the GL contents, new subdivisions of GL-containing plants are suggested. It was shown that only a limited number of the reported ca 130 GLs are available in fair quantities, acceptable for further investigation of the biological potential. In recent years, degradation products of a limited number of GLs (e.g., gluconasturtiin, glucoraphanin, glucomoringin), mostly isothiocyanates, have been found to possess real pharmacological activity. Some of the biological aspects of GLs and isothiocyanates which have been in recent focus are presented.


Glucosinolates Isothiocyanates Order Brassicales Biological activity 



Alzheimer’s disease




Angiosperm phylogeny group classification


Antioxidant response element


Branched-chain amino acids




Electrospray ionization and Fourier transform ion cyclotron resonance mass spectrometry


Gas chromatography–mass spectrometry






High-performance liquid chromatography


High-performance liquid chromatography–electrospray mass spectrometry










Nuclear factor (erythroid-derived 2)-like 2
















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Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  • Ivica Blažević
    • 1
    Email author
  • Sabine Montaut
    • 2
  • Franko Burčul
    • 3
  • Patrick Rollin
    • 4
  1. 1.Department of Organic Chemistry, Faculty of Chemistry and TechnologyUniversity of SplitSplitCroatia
  2. 2.Department of Chemistry and Biochemistry, Biomolecular Sciences ProgrammeLaurentian UniversitySudburyCanada
  3. 3.Department of Biochemistry, Faculty of Chemistry and TechnologyUniversity of SplitSplitCroatia
  4. 4.Université d’Orléans et CNRS, ICOAOrléansFrance

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