Polycystic Ovary Syndrome

Living reference work entry


Polycystic ovary syndrome (PCOS) is a common endocrinopathy affecting approximately 5–10 % of reproductive-age women. PCOS is considered the most common cause of anovulatory infertility. PCOS is widely accepted as a combination of ovulatory dysfunction, androgen excess, and polycystic ovaries with the exclusion of specific disorders that may lead to similar phenotypes. Genetic variants have also been identified which result in PCOS. PCOS is associated with insulin resistance, type 2 diabetes mellitus, dyslipidemia, and visceral obesity. The treatment of PCOS is multifaceted, including the use of oral contraceptives, insulin sensitizers, antiandrogen agents, and other medications; PCOS therapy is tailored to patient-specific physiological conditions and treatment goals.




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Authors and Affiliations

  1. 1.Division of EndocrinologyLenox Hill Hospital, Northwell HealthNew YorkUSA
  2. 2.Division of EndocrinologyNYU Langone Medical CenterNew YorkUSA
  3. 3.Perpetual Succour Hospital and Cebu Doctors’ University HospitalCebuPhilippines
  4. 4.Barnabas Health Medical GroupCliftonUSA

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