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Bioinformatic, Molecular, and Genetic Tools for Exploring Genome-Wide Responses to Hydrocarbons

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Cellular Ecophysiology of Microbe

Part of the book series: Handbook of Hydrocarbon and Lipid Microbiology ((HHLM))

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Abstract

The response profiles of bacteria to hydrocarbons in the wild can be directly assessed by high-throughput cDNA sequencing of metagenomes, tracking the fate or metabolism of labeled cells in the microbial community or can be indirectly inferred from the screening of mutant libraries for key genetic determinants. Transcriptome, proteome, and metabolome data are collected from homogeneous bacterial populations that are exposed to hydrocarbons under strictly controlled culturing conditions.

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Author information

Authors and Affiliations

  1. Centre for Bioinformatics and Computational Biology, Department of Biochemistry, University of Pretoria, Hillcrest, Pretoria, South Africa

    O. N. Reva & R. E. Pierneef

  2. Klinische Forschergruppe, Medizinische Hochschule Hannover, OE 6710, Hannover, Germany

    B. Tümmler

Authors
  1. O. N. Reva
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  2. R. E. Pierneef
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  3. B. Tümmler
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Corresponding author

Correspondence to O. N. Reva .

Editor information

Editors and Affiliations

  1. Consejo Superior de Investigaciones, Estacion Experimental del Zaidin, Granada, Spain

    Tino Krell

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Reva, O.N., Pierneef, R.E., Tümmler, B. (2017). Bioinformatic, Molecular, and Genetic Tools for Exploring Genome-Wide Responses to Hydrocarbons. In: Krell, T. (eds) Cellular Ecophysiology of Microbe. Handbook of Hydrocarbon and Lipid Microbiology . Springer, Cham. https://doi.org/10.1007/978-3-319-20796-4_33-1

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  • DOI: https://doi.org/10.1007/978-3-319-20796-4_33-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-20796-4

  • Online ISBN: 978-3-319-20796-4

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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