Techniques for facial aesthetic rejuvenation and enhancement are continuously evolving. The use of hyaluronic acid injectable fillers for rejuvenation is the second leading facial aesthetic procedure, after the use of injectable neuromodulator. The first step to achieve an optimal outcome in facial aesthetics is to understand the whole process of aging, such as bone reabsorption, atrophy of the fat compartments, muscle contraction, dental loss, and thinning of the skin. Hyaluronic acid filler is an important tool to achieve a global treatment of the face, since it is capable to restructure, to contour smoothly and to treat delicate areas as well. In this chapter we are going to describe facial assessment, indications, treatment planning, and procedures according to the anatomic area. Authors will explain the best technique and preferable hyaluronic acid to treat the forehead, temples, eyebrows, zygomatic and malar area, periocular region, chin, mandible, and perioral region.
- Face aging
- Volume loss
- Fat compartments
- Hyaluronic acid
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Andre P. Hyaluronic acid and its use as a rejuvenation agent in cosmetic dermatology. Semin Cutan Med Surg. 2004;23(4):218–22.
Bertucci V, Lynde CB. Current concepts in the use of small-particle hyaluronic acid. Plast Reconstr Surg. 2015;136(5 Suppl):132S–8S.
Borrell M, Leslie DB, Tezel A. Lift capabilities of hyaluronic acid fillers. J Cosmet Laser Ther. 2011;13(1):21–7.
Bosset S, Barre P, Chalon A, et al. Skin ageing clinical and histopathologic study of permanent and reducible wrinkles. Eur J Dermatol. 2002;23:247–52.
Braz AV, Aquino BO. Preenchimento do sulco nasojugal e da depressao infraorbital lateral com microcanula 30G. Surg Cosmet Dermatol. 2012;4(2):178–81.
Braz AV, Mukamal LV. Preenchimento labial com microcanula. Surg Cosmet Dermatol. 2011;3(3):257–60.
Braz AV, Sakuma TH. Midface rejuvenation an innovative technique to restore cheek volume. Dermatol Surg. 2012;38(1):118–20.
Braz AV, Mukamal LV, Costa DLM. Manejo cosmetico del tercio medio e inferior de la cara. In: Atamoros FP, Merino JE, editors. Dermatologia cosmetica. Cidade do Mexico: Elsevier Masson Doyma; 2011.
Braz AV, Louvain D, Mukamal LV. Combined treatment with botulinum toxin and hyaluronic acid to correct unsightly lateral chin depression. An Bras Dermatol. 2013;88(1):138–40.
Callan P, Goodman GJ, Liew S, et al. Efficacy and safety of a hyaluronic acid filler in subjects treated for correction of midface volume deficiency a 24 month study. Clin Cosmet Investig Dermatol. 2013;6:81–9.
Carruthers A, Carruthers J, Hardas B, et al. A validated lip fullness grading scale. Dermatol Surg. 2008;34(Suppl2):161–6.
Coleman SR. Structural fat grafting. St. Louis: Quality Medical Publishing; 2004.
Coleman SR, Grover R. The anatomy of the aging face volume loss and changes in 3-dimensional topography. Aesthet Surg J. 2006;26(S):S4–9.
de Maio M, Swift A, Signorini M, et al. Facial assessment and injection guide for botulinum toxin and injectable hyaluronic acid fillers focus on the upper face. Plast Reconstr Surg. 2017;140(2):265–76.
Donofrio LM. Fat distribution a morphologic study of the aging face. Dermatol Surg. 2000;26:1107–12.
El-Doyati M, Attia S, Saleh F, et al. Intrinsic aging vs. photoaging a comparative histopathological, immunohistochemical, and ultrastructural study of skin. Exp Dermatol. 2002;11:398–405.
Ellebogen R, Youn A, Yamini D, Svehlak S. The volumetric face lift. Aesthet Surg J. 2004;24:514–22.
Fenske NA, Lober CW. Structural and functional changes of normal aging skin. J Am Acad Dermatol. 1986;15:571–85.
Fulton JE Jr, Rahimi AD, Helton P, et al. Lip rejuvenation. Dermatol Surg. 2000;26:470–4.
Ghavami A, Pessa JE, Janis J, et al. The orbicularis retaining ligament of the medial orbit: closing the circle. Plast Reconstr Surg. 2008;121(3):994–1101.
Guyuron B. The aging nose. Dermatol Clin. 1997;15:659–64.
Hirmand H. Anatomy and nonsurgical correction of the tear through deformity. Plast Reconstr Surg. 2010;125(2):699–708.
Hwang K, Nam YS, Kim DJ, et al. Surgical anatomy of retaining ligaments in the periorbital area. J Craniofac Surg. 2008;19(3):800–4.
Jones D, Murphy DK. Volumizing hyaluronic acid filler for midface volume deficit 2-year results from a pivotal single-blind randomized controlled study. Dermatol Surg. 2013;39(11):1602–12.
Klein AW. In search of the perfect lip. Dermatol Surg. 2005;31(11 Pt 2):1599–603.
Landau M, Fagien S. Science of hyaluronic acid beyond filling fibroblasts and their response to the extracellular matrix. Plast Reconstr Surg. 2015;136(5 Suppl):188S–95S.
Medelson BC, Muzaffar AR, Adams WP Jr. Surgical anatomy of the midcheek and malar mounds. Plast Reconstr Surg. 2002;110:885–911.
Moss CJ, Medelson BC, Taylor GI. Surgical anatomy of the ligamentous attachments in the temple and periorbital regions. Plast Reconstr Surg. 2000;105:1475–98.
Ozdemir R, Kilinc H, Unlu E, et al. Anatomicohistologic study of the retaining ligaments of the face and use in face lift retaining ligament correction and SMAS placation. Plast Reconstr Surg. 2002;110:1134–47.
Pessa JE. An algorithm of facial aging verification of Lambros’s theory by three-dimensional stereolithography, with reference to the pathogenesis of midfacial aging, scleral show, and the lateral suborbital through deformity. Plast Reconstr Surg. 2000;106:479–87.
Pessa JE, Zadoo VP, Mutimer KL, et al. Relative maxillary retrusion as a natural consequence of aging: combining skeletal and soft tissue changes into an integrated model of midfacial aging. Plast Reconstr Surg. 1998;102:205–12.
Pierre S, Liew S, Bernadin A. Basics of dermal filler rheology. Dermatol Surg. 2015;41(Suppl 1):S120–6.
Price RD, Berry MG, Navsaria HA. Hyaluronic acid the scientific and clinical evidence. J Plast Reconstr Aesthet Surg. 2007;60(10):1110–9.
Raspaldo H. Temporal rejuvenation with fillers global faceculpture approach. Dermatol Surg. 2012;38:261–5.
Raspaldo H, Gassia V, Niforos FR, et al. Global, 3-dimensional approach to natural rejuvenation part 1. Recommendation for volume restoration and the periocular area. J Cosmet Dermatol. 2012;11:279–89.
Reece EM, Pessa JE, Rohrich RJ. The mandibular septum anatomical observations of the jowls in aging-implications for facila rejuvenation. Plast Reconstr Surg. 2008;121(4):1414–20.
Rohrich RJ, Pessa JE, Ristow B. The youthful cheek and the deep medial fat compartment. Plast Reconstr Surg. 2008;121:2107–12.
Sarnoff DS, Saini R, Gotkin RH. Comparison of filling agents for for lip augmentation. Aesthet Surg J. 2008;28:556–63.
Shaw RB Jr, Kahn DM. Aging of the midface bony elements a three dimensional CT study. Plast Reconstr Surg. 2007;119:675–81.
Shaw RB, Katzel EB, Koltz PF, et al. Aging of the facial skeleton aesthetic implications and rejuvenation strategies. Plast Reconstr Surg. 2011;127:374–83.
Sherris DA, Larrabee WF. Anatomic considerations in rhytidectomy. Facial Plast Surg. 1996;12:215–22.
Swift A, Remington K. Beauthiphication a global approach to facial beauty. Clin Plast Surg. 2011;38:347–77.
Wang F, Garza LA, Kang S, et al. In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin. Arch Dermatol. 2007;143(2):155–63.
Weinkle S. Injection techniques for revolumization of the perioral region with hyaluronic acid. J Drugs Dermatol. 2010;9(4):367071.
Yang HM, Lee JG, Hu KS, et al. New anatomical insights on the course and branching patterns of the facial artery clinical implications of injectable treatments to the nasolabial fold and nasojugal groove. Plast Reconstr Surg. 2014;133(5):1077–82.
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Zimbres, S. (2018). Hyaluronic Acid Fillers: Codifying the Face for Foundation, Reconstruction, and Refinement. In: Issa, M., Tamura, B. (eds) Botulinum Toxins, Fillers and Related Substances. Clinical Approaches and Procedures in Cosmetic Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-20253-2_43-1
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-20253-2
Online ISBN: 978-3-319-20253-2
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