Photodynamic Therapy for Photodamaged Skin

  • Ana Carolina Junqueira Ferolla
  • Maria Claudia Almeida Issa
Living reference work entry
Part of the Clinical Approaches and Procedures in Cosmetic Dermatology book series (CAPCD)


Photodynamic therapy (PDT) is a well-established therapeutic modality for nonmelanoma skin cancer (NMSC). It is based on a photochemical reaction, which causes destruction of the target tissue associated with an inflammatory response. In the last years, PDT has been indicated for some dermatosis in cosmetic dermatology, such as acne, sebaceous hyperplasia, rosacea, and photoaging. Although PDT’s mechanism of action in these dermatoses is not totally clear, some histological studies had shown dermis remodeling induced by PDT in photodamaged skin. In this chapter, we are going to discuss about photoaging and PDT treatment, comparing literature review and authors’ experience.


Photodynamic therapy Photosensitizer Nonmelanoma skin cancer Actinic keratosis Basal cell carcinoma Bowen disease Photodamaged skin Collagen fibers Elastic fibers Skin remodeling Dermis Aging Photoaging Photorejuvenation Rejuvenation 


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Copyright information

© Springer International Publishing AG 2016

Authors and Affiliations

  • Ana Carolina Junqueira Ferolla
    • 1
  • Maria Claudia Almeida Issa
    • 2
  1. 1.Medical Ambulatory of SpecialtiesBarradasBrazil
  2. 2.Department of Clinical Medicine – DermatologyUniversidade Federal FluminenseIcarai – NiteróiBrazil

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