The Assessment and Management of Hypotension and Shock in the Poisoned Patient

  • Florian Eyer
Reference work entry


While several large-scaled multicenter studies have changed the approach to the diagnosis and treatment of hypotension and shock in septic patients in recent years, the evidence base for the appropriate management of circulatory failure in poisoned patients is much more precarious. Toxicological research is often limited to case reports, small case series, or animal studies and most clinical recommendations or treatment guidelines are based on expert consensus or even personal experience rather than on criteria of evidence-based medicine [1]. Additionally, there may be a significant reporting bias from positive cases responding to different treatments, including extraordinary resuscitation measures. However, given the infrequency of many of these poisoning events, the likelihood of confirmatory randomized controlled trials to prove effectiveness will be low [2].


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of Clinical ToxicologyKlinikum rechts der Isar – Technical University of MunichMunichGermany

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