Skip to main content

Management of Adnexal Masses

  • Living reference work entry
  • First Online:
  • 175 Accesses

Abstract

The differential diagnoses of an adnexal mass range from benign functional ovarian cysts to metastatic ovarian carcinoma. The goal of the clinician is to differentiate benign conditions from more serious life-threatening or malignant conditions. Work-up of an adnexal mass demands a thorough history and physical exam followed by gray-scale transvaginal ultrasonography (Givens et al. Am Fam Physician 2009;80(8):815–20). Findings that are suspicious for carcinoma include symptoms of bloating, increasing pelvic or abdominal pain, weight loss coupled with the presence of a solid component or complex mass, positive Doppler flow in the mass, thick septations, mural nodules, or presence of ascites. In an asymptomatic postmenarchial woman, [regardless of age] with an adnexal mass, transvaginal ultrasonography is the initial imaging study of choice (Guideline Summary. American College of Obstetricians and Gynecologists NGC.006539 2007 Jul reaffirmed 2011. https://www.guideline.gov/summaries/summary/12631. Assessed 2 Sept 2016). Simple ovarian “simple cysts” can be found routinely in both premenopausal and postmenopausal women (Healy et al. Menopause 2008;15(6):1109–14), and hemorrhagic corpus luteum cysts (3–5 cm in size) can occur in early (within 5 years of) menopause (Seungdamrong and Weiss. Fertil Steril 2007;88(5):1438 e1-2). A serum Ca-125 should not be used routinely in premenopausal women (US Preventive Service Task Force 2016; American College of Obstetricians and Gynecologists. Obstet Gynecol 2007;110(1):201–14).

This is a preview of subscription content, log in via an institution.

References

  • American College of Obstetricians and Gynecologists. Management of adnexal masses. Obstet Gynecol. 2007;110(1):201–14.

    Article  Google Scholar 

  • Givens V, Mitchell G, Harraway-Smith C, Reddy V, Maness L. Diagnosis and management of adnexal masses. Am Fam Physician. 2009;80(8):815–20.

    PubMed  Google Scholar 

  • Goff BA, Mandel L, Munt HG, Meancon CH. Ovarian cancer diagnosis. Cancer. 2000;89(10):2068–75.

    Article  CAS  PubMed  Google Scholar 

  • Grimes DA, Jones LB, Lopez LM, Schulz KF. Oral contraceptives for functional ovarian cysts. Cochrane Database Sys Rev. 2009;2:CD006134.

    Google Scholar 

  • Guideline Summary. American College of Obstetricians and Gynecologists NGC.006539 2007 Jul reaffirmed 2011. https://www.guideline.gov/summaries/summary/12631. Assessed 2 Sept 2016.

  • Healy DL, Bell R, Robertson DM, Jobling T, Oehler MK, Edwrds A, Shekleton P, Oldham J, Piessens S, Teoh M, Mamers P, Taylor N, Walker F. Ovarian status in healthy postmenopausal women. Menopause. 2008;15(6):1109–14.

    Article  PubMed  Google Scholar 

  • Hermans AJ, Kluivers KB, Wijnen MH, Bulten J, Massuger LF, Coppus SF. Diagnosis and treatment of adnexal masses in children and adolescents. Obstet Gynecol. 2015;125(3):611–5.

    Article  PubMed  Google Scholar 

  • Kinkel K, Hricak H, Lu Y, Tsuda K, Filly RA. US characterization of ovarian masses: a meta-analysis. Radiology. 2000;1217(3):803.

    Article  Google Scholar 

  • Kinkel K, Lu Y, Mihdizade A, Pelte MF, Hricak H. Indeterminate ovarian mass at US: incremental value of second imaging test for characterization-meta-analysis and Bayesian analysis. Radiology. 2005;236(1):85.

    Article  PubMed  Google Scholar 

  • Mitchell MD, Harraway-Smith C, Reddy A, Maness D. Diagnosis and management of adnexal masses. Am Fam Physician. 2009;80(8):815–20.

    PubMed  Google Scholar 

  • ModeRisk of malignancy in unilocular cystic tumors less than 10 centimeters in diameter. Obstet Gynecol. 2003;102(3):;594–9.

    Google Scholar 

  • Modesitt SC, Pavlik EJ, et al. Risk of malignancy in unilocular ovarian cystic tumors less than 10 centimeters in diameter. Obstct Gynecol. 2003;102(3):594–9.

    Google Scholar 

  • Nagell Jr V, Miler RW. Evaluation and management of ultrasonographically detected ovarian tumors in asymptomatic women. Obstet Gynecol. 2016;127:848.

    Article  PubMed  Google Scholar 

  • Olson SH, Mignonoe L, Nakraseive C, Caputo TA, Barakat RR, Harlap S. Symptoms of ovarian cancer. Obstet Gynecol. 2001;89(2):212–7.

    Google Scholar 

  • Patel MD, Goff B, Levine D, Falk S. UpToDate Ultrasound differentiation of benign versus malignant adnexal masses. www.uptodate.com. Last accessed 21 Sept 2016.

  • Royal College of Obstetricians and Gynaecologists (RCOG). Ovarian cysts in postmenopausal women, Green-top guideline No. 34. London: Royal College of Obstetricians and Gynaecologists; 2016. https://www.rcog.org.uk/globalassets/documents/guidelines/green-top-guidelines/gtg_34.pdf. Last accessed 14 Sept 2016.

    Google Scholar 

  • Seungdamrong A, Weiss G. Ovulation in a postmenopausal woman. Fertil Steril. 2007;88(5):1438.e1-2. Epub 2007 Feb 12.

    Article  PubMed  Google Scholar 

  • US Preventive Service Task Force. Final recommendation statement ovarian cancer: screening. July 2015 http://www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/ovarian-cancer-screening. Last assessed 14 Sept 2016.

  • Whitecar MP, Turner S, Higby MK. Adnexal masses in pregnancy: a review of 130 cases undergoing surgical management. Am J Obstet Gynecol. 1999;181(1):19–24.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Donna Shoupe .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing AG

About this entry

Cite this entry

Shoupe, D. (2016). Management of Adnexal Masses. In: Shoupe, D. (eds) Handbook of Gynecology. Springer, Cham. https://doi.org/10.1007/978-3-319-17002-2_92-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-17002-2_92-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Online ISBN: 978-3-319-17002-2

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics