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Germ Cell Tumors of the Ovaries

  • Living reference work entry
  • First Online:
Handbook of Gynecology

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Abstract

The basic classification of ovarian germ cell tumors has largely remained unchanged for several decades. Ovarian germ cell tumors develop from primordial germ and stem cells that differentiate into extraembryonal and somatic tissues. In most cases, benign and malignant ovarian germ cell tumors can be correctly diagnosed due to their characteristic morphologic profiles. Several immunohistochemical (IHC) markers are widely available and can significantly facilitate tumor typing of germ cell tumors, especially in high grade tumors or in atypical clinical scenarios. In this chapter, the clinicopathologic features of ovarian germ cell tumors will be reviewed, with emphasis on morphology and diagnostically useful IHC markers.

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Authors and Affiliations

  1. Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, 1161 21st Avenue South, MCN, C-2310A, Nashville, TN, 37232-2561, USA

    Mohamed Mokhtar Desouki

  2. Department of Pathology, University of California San Diego, 200 West Arbor Drive, MC 8720, Room 2-120, San Diego, CA, 92103, USA

    Oluwole Fadare

Authors
  1. Mohamed Mokhtar Desouki
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  2. Oluwole Fadare
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Corresponding author

Correspondence to Mohamed Mokhtar Desouki .

Editor information

Editors and Affiliations

  1. Department of Obstetrics and Gynecology and Family Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA

    Donna Shoupe

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© 2016 Springer International Publishing Switzerland

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Desouki, M., Fadare, O. (2016). Germ Cell Tumors of the Ovaries. In: Shoupe, D. (eds) Handbook of Gynecology. Springer, Cham. https://doi.org/10.1007/978-3-319-17002-2_64-1

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  • DOI: https://doi.org/10.1007/978-3-319-17002-2_64-1

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  • Publisher Name: Springer, Cham

  • Online ISBN: 978-3-319-17002-2

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