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Injectable Soft Tissues with Fibroblasts and Mesenchymal Cells

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Botulinum Toxins, Fillers and Related Substances

Part of the book series: Clinical Approaches and Procedures in Cosmetic Dermatology ((CAPCD,volume 4))

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Abstract

The use of autologous cells expanded from dermis or mesenchymal cells of adipose tissue has been studied, and it seems to be a promising technique in cosmetic dermatology. This process consists in the implant of expanded cells obtained either by excision of skin graft from occipital area or taken by liposuction from adipose abdominal tissue. Even skin flaps from plastic surgery can be used. These materials are sent to laboratory in appropriate growth medium and expanded after submitted to microbiological control. After about 45 days, it is possible to provide ten syringes containing about 1 million cells each for implants. The patient’s material is cryopreserved for further expansion and other injections. These cells are introduced in dermis by retro-injections. Improvement can be seen after the third week of implantation. This procedure is not approved in Brazil, and authors’ experience is based on their investigative studies. In this chapter, the concept, mechanism of action, and clinical applications are going to be discussed.

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Author information

Authors and Affiliations

  1. Universidade Federal Fluminense (UFF), Niterói, RJ, Brazil

    Neide Kalil Gaspar

  2. Hospital Universitário de Brasília, Brasília, Brazil

    Patricia Shu Kurizky

Authors
  1. Neide Kalil Gaspar
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  2. Patricia Shu Kurizky
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Corresponding author

Correspondence to Neide Kalil Gaspar .

Editor information

Editors and Affiliations

  1. Department of Clinical Medicine (Dermatology), Fluminense Federal University, Niterói, Rio de Janeiro, Brazil

    Maria Claudia Almeida Issa

  2. Clínicas Hospital of São Paulo of the University of Sao Paulo, Sao Paulo, Brazil

    Bhertha Tamura

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Gaspar, N.K., Kurizky, P.S. (2019). Injectable Soft Tissues with Fibroblasts and Mesenchymal Cells. In: Issa, M., Tamura, B. (eds) Botulinum Toxins, Fillers and Related Substances. Clinical Approaches and Procedures in Cosmetic Dermatology, vol 4. Springer, Cham. https://doi.org/10.1007/978-3-319-16802-9_31

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  • DOI: https://doi.org/10.1007/978-3-319-16802-9_31

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-16801-2

  • Online ISBN: 978-3-319-16802-9

  • eBook Packages: MedicineReference Module Medicine

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