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Lasers, Lights and Other Technologies pp 473–485Cite as

Transepidermal Drug Delivery and Photodynamic Therapy

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Abstract

Transepidermal drug delivery (TED) has been used with the aim to increase drug penetration into the skin, and its association with photodynamic therapy (PDT) is described for nonmelanoma skin cancer, porokeratosis, and photorejuvenation treatment. TED with PDT has been reported with fractional ablative methods (ablative laser and ablative radiofrequency), as well as with non-ablative lasers and with microneedles. TED with PDT is considered an effective method for actinic keratosis (field of cancerization) and for photorejuvenation.

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Authors and Affiliations

  1. Universidade Federal Fluminense, Niterói, RJ, Brazil

    Marianna Tavares Fernandes Pires & Livia Roale Nogueira

  2. Department of Clinical Medicine – Dermatology, Fluminense Federal University, Praia de Icarai 139, Niterói, RJ, 702, Brazil

    Maria Claudia Almeida Issa

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  1. Marianna Tavares Fernandes Pires
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  2. Livia Roale Nogueira
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  3. Maria Claudia Almeida Issa
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Correspondence to Marianna Tavares Fernandes Pires .

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Editors and Affiliations

  1. Department of Clinical Medicine – Dermatology, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil

    Maria Claudia Almeida Issa

  2. Clínicas Hospital of São Paulo of the University of Sao Paulo, Sao Paulo, São Paulo, Brazil

    Bhertha Tamura

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Pires, M.T.F., Nogueira, L.R., Issa, M.C.A. (2018). Transepidermal Drug Delivery and Photodynamic Therapy. In: Issa, M., Tamura, B. (eds) Lasers, Lights and Other Technologies. Clinical Approaches and Procedures in Cosmetic Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-16799-2_36

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  • DOI: https://doi.org/10.1007/978-3-319-16799-2_36

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