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Translational Research

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Encyclopedia of Creativity, Invention, Innovation and Entrepreneurship

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Synonyms

Translational medicine; Translational science

Definition

The terms translational research (TR), translational medicine, and translational science are currently seeing widespread usage in a variety of biomedical and health research fields. Yet, they remain slippery concepts. Indeed, TR has been used to describe research and development activities taking place anywhere in the biomedical innovation process, from animal studies to verify hypotheses about the molecular mechanisms of disease or physiology to health outcomes or health technology assessment studies. Most often, however, TR is used by biomedical actors to designate studies performed to validate hypotheses leading to short-term therapeutic or diagnostic innovations. This includes studies with animals, in vitro cell cultures, biomarker discovery, and validation studies but also early clinical trials up to proof of concept (Khoury et al. 2007; NCI 2007; Wehling 2010).

Figure 1offers a model of the research ad...

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Author information

Authors and Affiliations

  1. Science-Metrix, Montréal, Canada

    Etienne Vignola-Gagné

  2. Department Innovation Systems, Center for Innovation Systems and Policy, AIT Austrian Institute of Technology, Vienna, Austria

    Peter Biegelbauer

Authors
  1. Etienne Vignola-Gagné
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  2. Peter Biegelbauer
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Corresponding author

Correspondence to Etienne Vignola-Gagné .

Editor information

Editors and Affiliations

  1. Department of Information Systems and Technology, Management, European Union Research Center, GWU School of Business, The George Washington University, Washington, DC, USA

    Elias G. Carayannis

Section Editor information

  1. Unit for Quality Enhancement (UQE), University of Applied Arts Vienna, Vienna, Austria

    David F. J. Campbell

  2. Faculty for Interdisciplinary Studies (iff), Institute of Science Communication and Higher Education Research (WIHO), Alpen-Adria-University Klagenfurt, Vienna, Austria

    David F. J. Campbell

  3. Department of Political Science, University of Vienna, Vienna, Austria

    David F. J. Campbell

  4. Department for Continuing Education Research and Educational Management, Centre for Educational Management and Higher Education Development, Danube University Krems, Krems, Austria

    David F. J. Campbell

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Vignola-Gagné, E., Biegelbauer, P. (2020). Translational Research. In: Carayannis, E.G. (eds) Encyclopedia of Creativity, Invention, Innovation and Entrepreneurship. Springer, Cham. https://doi.org/10.1007/978-3-319-15347-6_338

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