PTSD and Bipolar Disorder: Approaches to Pharmacology, Psychotherapy, and Psychoeducation

  • Laura BajorEmail author
  • Jeffrey Lucero
  • Jenny Melguizo
  • Edwin Raffi
  • Dana Wang
Reference work entry


The treatment of individuals with comorbid PTSD and bipolar disorder involves distinct challenges that should be approached in a stepwise fashion. Treatment is best accomplished in a collaborative manner that takes into account an individual’s goals and values. This begins with comprehensive diagnostic assessment based on a thorough longitudinal history in addition to noting current presentation. Treatment planning must take into account risk factors such as mood switching with SSRIs and also must consider disorders that are frequently comorbid in individuals with bipolar disorder (e.g., substance abuse, metabolic disorder).


Bipolar disorder Prevalence Comorbidity Psychopharmacology 

List of Abbreviations


Clinician administered PTSD scale


Cognitive behavioral therapy


Cognitive processing therapy


Diabetes mellitus type 2


Epidemiological catchment area


Food and Drug Administration


National Comorbidity Study


Prolonged exposure


Post-traumatic stress disorder


Second-generation antipsychotic


Selective serotonin reuptake inhibitor


Systematic treatment enhancement program for bipolar disorder


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Copyright information

© Springer International Publishing Switzerland (outside the USA) 2016

Authors and Affiliations

  • Laura Bajor
    • 1
    • 2
    Email author
  • Jeffrey Lucero
    • 3
  • Jenny Melguizo
    • 3
  • Edwin Raffi
    • 3
  • Dana Wang
    • 3
  1. 1.Mental Health ServiceVA Boston Healthcare SystemJamaica PlainUSA
  2. 2.Psychiatry DepartmentHarvard Medical SchoolBostonUSA
  3. 3.Mental Health ServiceVA Boston Healthcare SystemBrocktonUSA

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