Abstract
In the last 25 years, intestinal transplantation moved from an experimental procedure to an established treatment option for patients with irreversible intestinal failure and life-threatening complication of total parenteral nutrition. Intestinal transplantation is the only treatment that can potentially cure the baseline disease and reestablish the normal physiology and anatomy for those patients (Abu-Elmagd, Gastroenterology 130:132–137, 2006). Over the last 20 years, there have been significant advances in immunosuppression regimens leading to excellent short-term outcomes. However, chronic rejection persists as one of the major causes of graft loss (Grant et al, Ann Surg 241:607–613, 2005). A more complete understanding of the intestinal immunology and its association with graft failure continues to evolve. In addition to the immunological risks, intestinal retransplantation is one of the most challenging surgical procedures in the field.
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Vianna, R., Beduschi, T. (2018). Intestine Retransplantation in the Intestine or Liver-Intestine Recipient. In: Dunn, S., Horslen, S. (eds) Solid Organ Transplantation in Infants and Children. Organ and Tissue Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-07284-5_26
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DOI: https://doi.org/10.1007/978-3-319-07284-5_26
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