Skip to main content

Convergence of Nanotechnology and Biotechnology

  • Reference work entry
  • First Online:

Abstract

This chapter is devoted to discussing the engineering and exploitation of life processes in artificial systems, the importance of value creation, and examples applying nanobiotechnology to solve current technical problems in environment and health. Understanding the process of life is a crucial step in the design and application of nanobiological systems. This naturally links an understanding of how life formed and evolved to how life processes can be engineered and purposefully harnessed. The union of nanotechnology and biotechnology has culminated in a new discipline, nanobiotechnology, through the synergistic leveraging of fundamental control of chemical, physical, and biological processes. Nanobiotechnology has, in turn, enabled both biologists to explore biochemical networks to develop a better understanding of life processes and engineers to propose an alternative approach to conventional fabrication technology. Because nanobiotechnology employs knowledge from both engineering and life science, methodology in both disciplines must be adapted to take full advantage of the opportunity to develop and demonstrate new ideas. The greatest challenge to achieving the full potential of nanobiotechnology is the successful transition from a bench-scale demonstration to the development and deployment of an economic technology. Presented are concepts and methodologies currently being exercised to advance laboratory achievements into solutions to environmental, health, and societal challenges.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   699.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD   949.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  • Borgnia M, Nielsen S, Engel A, Agre P (1999) Cellular and molecular biology of the aquaporin water channels. Annu Rev Biochem 68(1):425–458

    Article  Google Scholar 

  • Chikofsky EJ, Cross JH (1990) Reverse engineering and design recovery: a taxonomy. IEEE Softw 7(1):13–17

    Article  Google Scholar 

  • Chisti Y (2007) Biodiesel from microalgae. Biotechnol Adv 25(3):294–306

    Article  Google Scholar 

  • Choi HJ, Montemagno CD (2005) Artificial organelle: ATP synthesis from cellular mimetic polymersomes. Nano Lett 5(12):2538–2542

    Article  Google Scholar 

  • Davis MM, Butchart AT, Coleman MS, Singer DC, Wheeler JR, Pok A, Freed GL (2010) The expanding vaccine development pipeline, 1995–2008. Vaccine 28(5):1353–1356

    Article  Google Scholar 

  • Doudna JA, Lorsch JR (2005) Ribozyme catalysis: not different, just worse. Nat Struct Mol Biol 12(5):395–402

    Article  Google Scholar 

  • Douglas RG, Sadoff J, Samant V (2008) The vaccine industry. In: Vaccines, vol 37, 5th edn. Saunders, New York

    Google Scholar 

  • Drake JW (1991) A constant rate of spontaneous mutation in DNA-based microbes. Proc Natl Acad Sci U S A 88(16):7160–7164

    Article  Google Scholar 

  • Drexler KE (1992) Nanosystems: molecular machinery, manufacturing, and computation. Wiley, New York

    Google Scholar 

  • Ellington AD, Szostak JW (1990) In vitro selection of RNA molecules that bind specific ligands. Nature 346(6287):818–822

    Article  Google Scholar 

  • Emerson RW, Cabot JE (1883) The works of Ralph Waldo Emerson: lectures and biographical sketches. Houghton, Mifflin, Boston

    Google Scholar 

  • Erickson D, Li D (2004) Integrated microfluidic devices. Anal Chim Acta 507(1):11–26

    Article  Google Scholar 

  • Feynman RP (1960) There’s plenty of room at the bottom. Eng Sci 23(5):22–36

    Google Scholar 

  • Fischetti M (2011) Computers vs. brains. Sci Am 305(5):104

    Article  Google Scholar 

  • Haszeldine RS (2009) Carbon capture and storage: how green can black be? Science 325(5948):1647–1652

    Article  Google Scholar 

  • Hermanson GT (2013) Bioconjugate techniques, 3rd edn. Academic, Amsterdam

    Google Scholar 

  • Jacobson I, Lindström F (1991) Reengineering of old systems to an object-oriented architecture. In: ACM SIGPLAN Notices 26(11):340–350

    Google Scholar 

  • Jones R (2008) Why nanotechnology needs better polymer chemistry. Nat Nanotechnol 3(12):699–700

    Article  Google Scholar 

  • Kimura M (1968) Evolutionary rate at the molecular level. Nature 217(5129):624–626

    Article  Google Scholar 

  • Kitano H (2001) Foundations of systems biology. MIT Press, Cambridge

    Google Scholar 

  • Klussmann S (2006) The aptamer handbook: functional oligonucleotides and their applications. Wiley, Weinheim

    Book  Google Scholar 

  • Kruger K, Grabowski PJ, Zaug AJ, Sands J, Gottschling DE, Cech TR (1982) Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena. Cell 31(1):147–157

    Article  Google Scholar 

  • Luisi PL (2006) The emergence of life: from chemical origins to synthetic biology. Cambridge University Press, Cambridge

    Book  Google Scholar 

  • Lynch M (2010) Evolution of the mutation rate. Trends Genet 26(8):345–352

    Article  Google Scholar 

  • Mayer G (2009) Nucleic acid and peptide aptamers: methods and protocols. Humana Press, New York

    Book  Google Scholar 

  • Mazzola L (2003) Commercializing nanotechnology. Nat Biotechnol 21(10):1137–1143

    Article  Google Scholar 

  • Miller JH (1996) Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repair. Annu Rev Microbiol 50(1):625–643

    Article  Google Scholar 

  • Oparin AI (2003) The origin of life. Courier Dover Publications, New York

    Google Scholar 

  • Panyam J, Labhasetwar V (2003) Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev 55(3):329–347

    Article  Google Scholar 

  • Roco MC (2003a) Nanotechnology: convergence with modern biology and medicine. Curr Opin Biotechnol 14(3):337–346

    Article  Google Scholar 

  • Roco MC (2003b) Broader societal issues of nanotechnology. J Nanoparticle Res 5(3–4):181–189

    Article  Google Scholar 

  • Sniegowski PD, Gerrish PJ, Johnson T, Shaver A (2000) The evolution of mutation rates: separating causes from consequences. Bioessays 22(12):1057–1066

    Article  Google Scholar 

  • Sun C, Lee JS, Zhang M (2008) Magnetic nanoparticles in MR imaging and drug delivery. Adv Drug Deliv Rev 60(11):1252–1265

    Article  Google Scholar 

  • Szostak JW, Bartel DP, Luisi PL (2001) Synthesizing life. Nature 409(6818):387–390

    Article  Google Scholar 

  • Tao H, Lee SC, Moeller A, Roy RS, Siu FY, Zimmermann J, Stevens RC, Potter CS, Carragher B, Zhang Q (2013) Engineered nanostructured beta-sheet peptides protect membrane proteins. Nat Methods 10(8):759–761

    Article  Google Scholar 

  • Wang H, Oster G (1998) Energy transduction in the F1 motor of ATP synthase. Nature 396(6708):279–282

    Article  Google Scholar 

  • Wendell D, Todd J, Montemagno C (2010) Artificial photosynthesis in ranaspumin-2 based foam. Nano Lett 10(9):3231–3236

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Hyo-Jick Choi or Carlo D. Montemagno .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this entry

Cite this entry

Choi, HJ., Montemagno, C.D. (2016). Convergence of Nanotechnology and Biotechnology. In: Bainbridge, W., Roco, M. (eds) Handbook of Science and Technology Convergence. Springer, Cham. https://doi.org/10.1007/978-3-319-07052-0_65

Download citation

Publish with us

Policies and ethics