Skip to main content

Intravascular OCT

  • Reference work entry
Optical Coherence Tomography

Abstract

Since the first coronary angioplasty was performed in the late 1970s, imaging has played a central role in percutaneous coronary intervention (PCI). Today more than three million PCI procedures are performed worldwide to expand narrowed arteries and to clear blood clots that can cause debilitating symptoms of myocardial ischemia or fatal heart attacks. Although X-ray angiography is still the workhorse imaging modality in the field of interventional cardiology, intravascular imaging has become an indispensable tool for guiding complex PCI procedures. Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are the two most commonly used catheter-based imaging technologies in coronary procedures. Since the first commercial intravascular OCT systems were introduced in Japan and the European Union in 2004 and in the United States in 2009, the application of intravascular OCT has grown rapidly [3, 15, 16].

This chapter begins by outlining the motivation for the development of intravascular imaging technologies and tracing the evolution of intravascular OCT technology. The basics of OCT image acquisition and interpretation are discussed next in the context of current clinical applications of intracoronary OCT. The chapter ends with a summary of the trends in the field that likely to influence the future of intravascular OCT technology.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 299.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 449.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. P. Barlis, J. Tanigawa, C. Di Mario, Eur. Heart J. 28, 2319 (2007)

    Article  Google Scholar 

  2. P. Barlis, J.M. Schmitt, EuroIntervention 4, 529 (2009)

    Article  Google Scholar 

  3. H.G. Bezerra, M.A. Costa, G. Guagliumi, A.M. Rollins, D.I. Simons, JACC Cardiovasc. Interv. 2, 1035 (2009)

    Article  Google Scholar 

  4. B.E. Bouma, G.J. Tearney, H. Yabushita, M. Shishkov, C.R. Kauffman, D. DeJoseph, B.D. MacNeill, S.L. Hausler, H.T. Aretz, E.F. Halpern, I.K. Jang, Heart 89, 317 (2003)

    Article  Google Scholar 

  5. M.E. Brezinski, G.J. Tearney, B.E. Bouma, J.A. Izatt, M.R. Hee, E.A. Swanson, J.F. Southern, J.G. Fujimoto, Circulation 93, 1206 (1996)

    Article  Google Scholar 

  6. S. Cook, P. Wenaweser, M. Togni, M. Billinger, C. Morger, C. Seiler, R. Vogel, O. Hess, B. Meier, S. Windecker, Circulation 115, 2426 (2007)

    Article  Google Scholar 

  7. D.E. Cutlip, D.S. Baim, K.K.L. Ho, J.J. Popma, A.J. Lansky, D.J. Cohen, J.P. Carrozza, M.S. Chauhan, O. Rodriguez, R.E. Kuntz, Circulation 102, 1967 (2001)

    Article  Google Scholar 

  8. P. de Jaegere, H. Mudra, H. Figulla, Y. Almagor, S. Doucet, I. Penn, A. Columbo, C. Hamm, A. Bartorelli, M. Rothman, M. Nobuyoshi, T. Yamaguchi, V. Voudris, C. diMario, S. Makovski, D. Hausmann, S. Rowe, S. Rabinovich, M. Sunamura, G.A. van Es, Eur. Heart J. 19(1214) (1998)

    Google Scholar 

  9. J.G. Fujimoto, S.A. Boppart, G.J. Tearney, B.E. Bouma, C. Pitris, M.E. Brezinski, Heart 82, 128 (1999)

    Article  Google Scholar 

  10. U. Gerckens, L. Buellesfeld, E. MacNamara, E. Grube, Herz 28, 496 (2003)

    Article  Google Scholar 

  11. S.D. Giattina, B.K. Courtney, P.R. Herz, M. Harman, S. Shortkroff, D.L. Stamper, B. Liu, J.G. Fujimoto, M.E. Brezinski, Int. J. Cardiol. 107, 400 (2006)

    Article  Google Scholar 

  12. N. Gonzalo, H.M. Garcia-Garcia, P.W. Serruys, K.H. Commissaris, H. Bezerra, P. Gobbens, M. Costa, E. Regar, EuroIntervention 5, 224 (2009)

    Article  Google Scholar 

  13. E. Grube, U. Gerckens, L. Buellesfeld, P.J. Fitzgerald, Circulation 106, 2409 (2002)

    Article  Google Scholar 

  14. G. Guagliumi, G. Musumeci, V. Sirbu, H.G. Bezerra, N. Suzuki, L. Fiocca, A. Matiashvili, N. Lortkipanidze, A. Trivisonno, O. Valsecchi, G. Biondi-Zoccai, M.A. Costa, JACC Cardiovasc. Interv. 3, 531 (2010)

    Article  Google Scholar 

  15. G. Guagliumi, T. Akasaka, V. Sirbu, T. Kubo, Optical coherence tomography, Chapter 60, in Textbook of Interventional Cardiology, ed. by E.J. Topol, P.S. Teirstein (Elsevier, Philadelphia, 2012)

    Google Scholar 

  16. G. Guagliumi, V. Sirbu, C. Petroff, D. Capodanno, G. Musumeci, H. Yamamoto, A. Elbasiony, C. Brushett, A. Matiashvili, N. Lortkipanidze, O. Valsecchi, H.G. Bezerra, J.M. Schmitt, Volumetric assessment of lesion severity with optical coherence tomography: relationship with fractional flow reserve. EuroIntervention 8, 1172–1181 (2013)

    Article  Google Scholar 

  17. I.K. Jang, B.E. Bouma, D.H. Kang, S.J. Park, S.W. Park, K.B. Seung, K.B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S.L. Houser, H.T. Aretz, G.J. Tearney, S.A. Boppart, G.J. Tearney, J. Am. Coll. Cardiol. 39, 604 (2002)

    Article  Google Scholar 

  18. I.K. Jang, G.J. Tearney, B. MacNeill, M. Takano, F. Moselewski, N. Iftima, M. Shishkov, S.L. Houser, H.T. Aretz, E.F. Halpern, B.E. Bouma, Circulation 111, 1551 (2005)

    Article  Google Scholar 

  19. T. Kubo, T. Imanishi, S. Takarada, A. Kuroi, S. Ueno, T. Yamano, T. Tanimoto, Y. Matsuo, T. Masho, K. Tsuda, Y. Tomobuchi, T. Akasaka, J. Am. Coll. Cardiol. 50, 933 (2007)

    Article  Google Scholar 

  20. T. Kume, T. Akasaka, T. Kawamoto, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, K. Yoshida, Circ. J. 29, 903 (2005)

    Article  Google Scholar 

  21. T. Kume, T. Akasaka, T. Kawamoto, Y. Ogasawara, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, K. Yoshida, Am. J. Cardiol. 97, 1713 (2006)

    Article  Google Scholar 

  22. T. Kume, T. Akasaka, T. Kawamoto, H. Okura, N. Watanabe, E. Toyota, Y. Neishi, R. Sukmawan, Y. Sadahira, K. Yoshida, Am. Heart J. 152, e1 (2006)

    Article  Google Scholar 

  23. D. Levitz, L. Thrane, M. Frosz, P. Andersen, C. Andersen, S. Andersson-Engels, J. Valanciunaite, J. Swartling, P. Hansen, Opt. Express 12(249) (2004)

    Google Scholar 

  24. B.D. MacNeill, I.K. Jang, B.E. Bouma, N. Iftimia, M. Takano, H. Yabushita, M. Shiskov, C.R. Kauffman, S.L. Houser, H.T. Aretz, D. DeJoseph, E.F. Halpern, G.J. Tearney, J. Am. Coll. Cardiol. 44, 972 (2004)

    Article  Google Scholar 

  25. G.S. Mintz, S.E. Nissen, W.D. Anderson, S.R. Bailey, R. Erbel, P.J. Fitzgerald, F.J. Pinto, K. Rosenfield, R.J. Siegel, E.M. Tuzcu, P.G. Yock, R.A. O’Rourk, J. Abrams, E.R. Bates, B.R. Brodie, P.S. Douglas, G. Gregoratos, M.A. Hlatky, J.S. Hochman, S. Kaul, C.M. Tracy, D.D. Waters, W.L. Winters, J. Am. Coll. Cardiol. 37, 1478 (2001)

    Article  Google Scholar 

  26. A. Murata, D. Wallace-Bradley, A. Tellez, C. Alviar, M. Aboodi, A. Sheehy, L. Coleman, L. Perkins, G. Nakazawa, G. Mintz, G.L. Kaluza, R. Virmani, J. Am. Coll. Cardiol. Img. 3, 76 (2010)

    Article  Google Scholar 

  27. J.A. Ormiston, P.W. Serruys, E. Regar, D. Dudek, L. Thuesen, M.W. Webster, Y. Onuma, H.M. Garcia-Garcia, R. McGreevy, S. Veldhof, Lancet 371, 899 (2008)

    Article  Google Scholar 

  28. F. Prati, G. Guagliumi, G.S. Mintz, M. Costa, E. Regar, T. Akasaka, P. Barlis, G.J. Tearney, I.K. Jang, E. Arbustini, H.G. Bezerra, Y. Osaki, N. Bruining, D. Dudek, M. Radu, A. Erglis, P. Motreff, F. Alfonso, K. Toutouzas, N. Gonzalo, P.W.J. Serruys, C. Di Mario et al., Eur. Heart J. 10, 1093 (2012)

    Google Scholar 

  29. J. Rieber, O. Meissner, G. Babaryka, S. Reim, M. Oswald, A. Koenig, T.M. Schiele, M. Shapiro, K. Theisen, M.F. Reiser, V. Klauss, U. Hoffmann, Coron. Artery Dis. 17, 425 (2006)

    Article  Google Scholar 

  30. T. Sawada, J. Shite, H.M. Garcia-Garcia, T. Shinke, S. Watanabe, H. Otake, D. Matsumoto, Y. Tanino, D. Ogasawara, H. Kawamori, H. Kato, N. Miyoshi, M. Yokoyama, P.W. Serruys, K. Hirata, Eur. Heart J. 29, 1136 (2008)

    Article  Google Scholar 

  31. J.M. Schmitt, R. Huber, J.G. Fujimoto, Chapter 28: Limiting ischemia with fast fourier-domain imaging, in Optical Coherence Tomography in Cardiovascular Research, ed. by E. Regar, P.W. Serruys, (Taylor and Francis, London, 2006), pp. 256–266

    Google Scholar 

  32. J.M. Schmitt, U.S. Patent 7,916,387, issued 29 March 2011

    Google Scholar 

  33. P.W. Serruys, J.A. Ormiston, Y. Onumo, E. Regar, N. Gonzalo, H.M. Garcia-Garcia, K. Nieman, N. Bruining, C. Dorange, K. Miguel-Hebert, S. Veldhof, M. Webster, L. Thuesen, D. Dudek, Lancet 373, 897 (2009)

    Article  Google Scholar 

  34. Y. Shiono, H. Kitabata, T. Kubo, T. Masuno, S. Ohta, Y. Ozaki, H. Sougawa, M. Orii, K. Shimamura, K. Ishibashi, K. Komukai, T. Tanimoto, T. Yamaguchi, K. Hirata, M. Mizukoshi, T. Imanishi, T. Akasaka, Circ. J. 76, 2218 (2012)

    Article  Google Scholar 

  35. V. Sirbu, G. Guagliumi, G. Musumeci, Eur. Heart J. 29(suppl), 127 (2008)

    Google Scholar 

  36. H.C. Stary, A.B.. Chandler, R.E. Dinsmore, V. Fuster, S. Glagov, W. Insull, M.E. Rosenfeld, C.J. Schwartz, W.D. Wagner, R.W. Wissler, Arterioscler. Thromb. Vasc. Biol. 15, 1512 (1995)

    Article  Google Scholar 

  37. G.W. Stone, A. Maehara, A.J. Lansky, B. de Bruyne, E. Cristea, G.S. Mintz, R. Mehran, J. McPherson, N. Farhat, S.P. Marso, H. Parise, B. Templin, R. White, Z. Zhang, P.W. Serruys, N. Engl. J. Med. 364, 226 (2011)

    Article  Google Scholar 

  38. A. Tanaka, T. Imanishi, H. Kitabata, T. Kubo, S. Takarada, T. Tanimoto, A. Kuroi, H. Tsujioka, H. Ikejima, S. Ueno, H. Kataiwa, K. Okouchi, M. Kashiwaghi, H. Matsumoto, K. Takemoto, N. Nakamura, K. Hirata, M. Mizukoshi, T. Akasaka, Circulation 107, 118 (2008)

    Google Scholar 

  39. S. Tanimoto, P.W. Serruys, L. Thuesen, D. Dudek, B. deBruyne, B. Chevalier, J.A. Ormiston, Catheter. Cardiovasc. Interv. 70, 515 (2007)

    Article  Google Scholar 

  40. G.J. Tearney, H. Yabushita, S.L. Houser, H.T. Aretz, I.K. Jang, K.H. Schlendorf, C.R. Kauffman, M. Shishkov, E.F. Halpern, B.E. Bouma, Circulation 107, 113 (2003)

    Article  Google Scholar 

  41. G.J. Tearney, E. Regar, T. Akasaka, T. Adriaenssens et al., J. Am. Coll. Cardiol. 59, 1058 (2012)

    Article  Google Scholar 

  42. M. Terashima, S. Rathore, Y. Suzuki, Y. Nakayama, H. Kaneda, K. Nasu, M. Habara, O. Katoh, T. Suzuki, J. Invasive Cardiol. 21, 602 (2009)

    Google Scholar 

  43. F.J. van der Meer, D.J. Faber, D.M. Baraznji Sassoon, M.C. Aalders, G. Pasterkamp, T.G. van Leeuwen, IEEE Trans. Med. Imaging 24, 1369 (2005)

    Article  Google Scholar 

  44. G. van Soest, T. Goderie, E. Regar, S. Koljenovic, G.L. van Leenders, N. Gonzalo, S. van Noorden, T. Okamura, B.E. Bouma, G.J. Tearney, J.W. Oosterhuis, P.W. Serruys, A.F. van der Steen, J. Biomed. Opt. 15, 011105 (2010)

    Article  Google Scholar 

  45. R. Virmani, F.D. Kolodgie, A.P. Burke, A. Farb, S.M. Schwartz, Arterioscler. Thromb. Vasc. Biol. 20, 1262 (2000)

    Article  Google Scholar 

  46. R. Virmani, A.P. Burke, A. Farb, F.D. Kolodgie, J. Am. Coll. Cardiol. 47, C13 (2006)

    Article  Google Scholar 

  47. C. Xu, J.M. Schmitt, S.G. Carlier, R. Virmani, J. Biomed. Opt. 13, 034003 (2008)

    Article  ADS  Google Scholar 

  48. H. Yabushita, B.E. Bouma, S.L. Houser, H.T. Aretz, I.K. Jang, K.H. Schlendorf, C.R. Kauffmman, M. Shishkov, D.H. Kang, E.F. Halpern, G.J. Tearney, Circulation 106, 1640 (2002)

    Article  Google Scholar 

  49. S.H. Yun, G.J. Tearney, B.J. Vakoc, M. Shiskov, Y.O. Wang, A.E. Desjardins, M.J. Suter, R.D. Chan, J.A. Evans, I.K. Jang, N.S. Nishioka, J.F. deBoer, B.E. Bouma, Nat. Med. 12, 1429 (2006)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Joseph M. Schmitt .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this entry

Cite this entry

Schmitt, J.M., Adler, D., Xu, C. (2015). Intravascular OCT. In: Drexler, W., Fujimoto, J. (eds) Optical Coherence Tomography. Springer, Cham. https://doi.org/10.1007/978-3-319-06419-2_74

Download citation

Publish with us

Policies and ethics