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Hemostasis Models: Bleeding Models

  • Shaker A. Mousa
Reference work entry

Abstract

There is a delicate balance between thrombosis and hemostasis – primary hemostasis (platelet plug), secondary hemostasis (fibrin clot), and fibrinolysis. On the coagulation side, a balance between procoagulants and anticoagulants and pro-fibrinolytics and anti-fibrinolytics is crucial to maintain physiological hemostasis. Similarly, on the platelet side, a balance between endogenous platelet activators and inhibitors is also critical in the maintenance of hemostasis. When using either antiplatelet or anticoagulants to prevent or treat either arterial or venous thrombosis, a risk of bleeding exists due to the shift in the balance between thrombosis and hemostasis.

Keywords

Bleeding Time Antithrombotic Drug Primary Hemostasis Anesthetize Rabbit Small Mesenteric Artery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References and Further Reading

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Template Bleeding Time Method

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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.The Pharmaceutical Research InstituteAlbany College of Pharmacy and Health SciencesAlbanyUSA

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