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Bioactive Compounds and Biological Activities of Curculigo Species

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Bioactive Compounds in the Storage Organs of Plants

Part of the book series: Reference Series in Phytochemistry ((RSP))

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Abstract

Curculigo species belongs to the family of Hypoxidaceae. These plants hold a significant position in the Chinese and Ayurvedic systems of medicine, treating ailments due to their various effects on humans. The traditional system of medicine used the extracts of Curculigo species as an aphrodisiac herb, to treat amenorrhea, jaundice, and arthritis. To determine the significance of the plant, we reviewed PubMed, Google Scholar, and Web of Science for literature on its geographical, phytochemical, and pharmacological uses. The major bioactive compounds isolated from Curculigo are phenolic glycosides, polysaccharides, lignans, and alkaloids. The rhizome and the whole plant extracts are reported to have neuroprotective, antioxidant, antiosteoporotic, and anticancer properties. Among the Curculigo species, Curculigo orchioides are well explored for their pharmacological properties. The traditional use of the extracts was scientifically proved using different model systems. However, pharmacological processes and pathways of action of active compounds of the Curculigo genus are unexplored. This chapter is a comprehensive summary of the properties of Curculigo species and their therapeutic uses.

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Abbreviations

5-HT:

5-hydroxytryptamine

ACE:

Angiotensin-converting enzyme

BDNF:

Brain-derived neurotrophic factor

CAT:

Catalase

CC:

Column chromatography

CMS:

Chronic moderate stress

DA:

Dopamine

DPPH:

1, 1-diphenyl-2-picryldydrazyl

FAB-MS:

Fast-atom bombardment mass spectrometry

GPX:

Glutathione peroxidase

GRD:

Glutathione reductase

HPLC:

High-performance liquid chromatography

HR ESI-MS:

High-resolution electrospray ionization mass spectroscopy

HR-MS:

High-resolution mass spectrometry

IR:

Infrared spectroscopy

NE:

Norepinephrine

NMDA:

N-Methyl-D-Aspartate

NMRS:

Nuclear magnetic resonance spectroscopy

SOD:

Superoxide dismutase

TLC:

Thin layer chromatography

UV-VIS:

Ultraviolet-visible spectroscopy

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Authors and Affiliations

  1. Nitte (Deemed to be University), Department of Environmental Health and Toxicology, Nitte University Centre for Science Education and Research (NUCSER), Deralakatte, Mangalore, KA, India

    Sharanya Kushalan, Khyahrii Aloysius S, Abigail Faith Rego & Smitha Hegde

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  1. Sharanya Kushalan
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  2. Khyahrii Aloysius S
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  3. Abigail Faith Rego
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  4. Smitha Hegde
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Correspondence to Smitha Hegde .

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Editors and Affiliations

  1. Department of Botany, Karnatak University, Dharwad, Karnataka, India

    Hosakatte Niranjana Murthy

  2. Research Center for the Development of Advanced Horticultural Technology, Chungbuk National University, Cheongju, Korea (Republic of)

    Kee Yoeup Paek

  3. Dept of Horticultural Science, Chungbuk National University, Cheongju, Korea (Republic of)

    So-Young Park

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Kushalan, S., Aloysius S, K., Rego, A.F., Hegde, S. (2023). Bioactive Compounds and Biological Activities of Curculigo Species. In: Murthy, H.N., Paek, K.Y., Park, SY. (eds) Bioactive Compounds in the Storage Organs of Plants. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-031-29006-0_50-1

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