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Myositis Ossificans

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Clinical Atlas of Bone SPECT/CT

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Abstract

Myositis ossificans (MO) is a benign condition characterized by heterotopic bone formation in soft tissues, predominantly muscles, and consists of posttraumatic (75%), nontraumatic, and congenital subtypes. Risk factors include traumatic brain injury and prolonged mechanical ventilation. The condition is caused by a dysregulation of local stem cells in response to tissue injury, leading to an inappropriate differentiation of fibroblasts into osteogenic cells. Posttraumatic MO is a benign and self-limiting condition, which progresses through parallel clinical, histopathologic, and radiographic stages, the three commonly described overlapping stages of evolution being early, intermediate, and mature. This chapter describes and illustrates the clinical characteristics, stages, and imaging findings of MO on X-ray, bone SPECT/CT, and MR.

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Authors and Affiliations

  1. Department of Nuclear Medicine and PET/CT, Sir H.N. Reliance Foundation Hospital, Mumbai, India

    Ujwal Bhure

  2. Department of Radiology and Nuclear Medicine, Luzerner Kantonsspital, Luzern, Switzerland

    Ujwal Bhure

  3. Department of Radiology and Nuclear Medicine, Luzerner Kantonsspital, Lucerne, Switzerland

    Klaus Strobel

  4. Division of Nuclear Medicine, MRI, Zurich, Switzerland

    Thomas F. Hany

Authors
  1. Ujwal Bhure
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  2. Thomas F. Hany
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  3. Klaus Strobel
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Corresponding author

Correspondence to Ujwal Bhure .

Editor information

Editors and Affiliations

  1. Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium

    Tim Van den Wyngaert

  2. Department of Nuclear Medicine, Royal Free London NHS Foundation Trust, London, UK

    Gopinath Gnanasegaran

  3. Department of Radiology and Nuclear Medicine, Luzerner Kantonsspital, Lucerne, Switzerland

    Klaus Strobel

Section Editor information

  1. CNI Molecular Imaging and University of Notre Dame, Sydney, Australia

    Hans Van der Wall

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Bhure, U., Hany, T.F., Strobel, K. (2023). Myositis Ossificans. In: Van den Wyngaert, T., Gnanasegaran, G., Strobel, K. (eds) Clinical Atlas of Bone SPECT/CT. Springer, Cham. https://doi.org/10.1007/978-3-031-26449-8_265

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  • DOI: https://doi.org/10.1007/978-3-031-26449-8_265

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-26448-1

  • Online ISBN: 978-3-031-26449-8

  • eBook Packages: MedicineReference Module Medicine

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