Skip to main content

Liposclerosing Myxofibrous Tumor of Femur

  • Reference work entry
  • First Online:
Clinical Atlas of Bone SPECT/CT

Abstract

Liposclerosing myxofibrous tumor (LSMFT) is a rare benign fibro-osseous lesion. Asymptomatic lesions may not require specific surgery, whereas symptomatic lesions are generally treated with curettage and bone graft with good prognosis. A small risk of malignant transformation remains, and follow-up is warranted. Characteristically seen on radiograph/CT as a well-defined osteolytic lesion with a thick sclerotic border and mild to moderately increased radiotracer activity in the lesion on a delayed phase of bone scintigraphy, SPECT/CT often helps in precise characterization of the lesion.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  • Barnds B, Grote C, Mettman D, Templeton K. Liposclerosing myxofibrous tumor in a patient with prostate cancer: a case report. JBJS Case Connect. 2019;9(4):e0411.

    Article  PubMed  Google Scholar 

  • Campbell K, Wodajo F. Case report: two-step malignant transformation of a liposclerosing myxofibrous tumor of bone. Clin Orthop Relat Res. 2008;466(11):2873–7.

    Article  PubMed  PubMed Central  Google Scholar 

  • Deel C, Hassell L. Liposclerosing myxofibrous tumor: a review. Arch Pathol Lab Med. 2016;140(5):473–6.

    Article  PubMed  Google Scholar 

  • Heim-Hall JM, Williams RP. Liposclerosing myxofibrous tumour: a traumatized variant of fibrous dysplasia? Report of four cases and review of the literature. Histopathology. 2004;45(4):369–76.

    Article  CAS  PubMed  Google Scholar 

  • Kim J, Chen W, Resnik C, Dilsizian V, Chen Q, Kimball AS. FDG uptake in liposclerosing myxofibrous tumor causes upstaging of Hodgkin lymphoma. Clin Nucl Med. 2015;40(4):325–7.

    Article  PubMed  Google Scholar 

  • Kransdorf MJ, Murphey MD, Sweet DE. Liposclerosing myxofibrous tumor: a radiologic-pathologic-distinct fibro-osseous lesion of bone with a marked predilection for the intertrochanteric region of the femur. Radiology. 1999;212(3):693–8.

    Article  CAS  PubMed  Google Scholar 

  • Ragsdale BD. Polymorphic fibro-osseous lesions of bone: an almost site-specific diagnostic problem of the proximal femur. Hum Pathol. 1993;24(5):505–12.

    Article  CAS  PubMed  Google Scholar 

  • Ragsdale BD, Sweet DE. Bone. In: Henson DE, Albores-Saavedra J, editors. The pathology of incipient neoplasia. Philadelphia: Saunders; 1986. p. 381–423.

    Google Scholar 

  • Regado ER, Garcia PB, Caruso AC, de Almeida AL, Aymore IL, Meohas W, et al. Liposclerosing myxofibrous tumor: a series of 9 cases and review of the literature. J Orthop. 2016;13(3):136–9.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ujwal Bhure .

Editor information

Editors and Affiliations

Section Editor information

Rights and permissions

Reprints and permissions

Copyright information

© 2023 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Bhure, U., Hany, T.F., Strobel, K. (2023). Liposclerosing Myxofibrous Tumor of Femur. In: Van den Wyngaert, T., Gnanasegaran, G., Strobel, K. (eds) Clinical Atlas of Bone SPECT/CT. Springer, Cham. https://doi.org/10.1007/978-3-031-26449-8_219

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-26449-8_219

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-26448-1

  • Online ISBN: 978-3-031-26449-8

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics