Abstract
Metastatic disease, myeloma, and lymphoma often present as multiple lesions in the spine, making the diagnosis of malignancy straightforward. In contrast, unifocal spine lesions may cause diagnostic uncertainty, and the differentiation between benign and malignant pathology can be challenging. This chapter discusses the imaging characteristics of common spine lesions and presents a classification system that may assist in differentiating aggressive from nonaggressive lesions. In addition, the Bone-RADS framework is introduced to help guide the management of patients with a solitary bone lesion based on its imaging features.
This is a preview of subscription content, log in via an institution to check access.
References
Aoki J, Watanabe H, Shinozaki T, Takagishi K, Ishijima H, Oya N, et al. FDG PET of primary benign and malignant bone tumors: standardized uptake value in 52 lesions. Radiology. 2001;219(3):774–7.
Caracciolo JT, Temple HT, Letson GD, Kransdorf MJ. A modified Lodwick-Madewell grading system for the evaluation of lytic bone lesions. AJR Am J Roentgenol. 2016;207(1):150–6.
Chang CY, Garner HW, Ahlawat S, Amini B, Bucknor MD, Flug JA, et al. Society of Skeletal Radiology- white paper. Guidelines for the diagnostic management of incidental solitary bone lesions on CT and MRI in adults: bone reporting and data system (Bone-RADS). Skelet Radiol. 2022;51(9):1743–64.
Miller TT. Bone tumors and tumorlike conditions: analysis with conventional radiography. Radiology. 2008;246(3):662–74.
Orguc S, Arkun R. Primary tumors of the spine. Semin Musculoskelet Radiol. 2014;18(3):280–99.
Paycha F, Girma A, Granier P. Démarche sémiologique en TEMP/TDM osseuse. Une approche diagnostique intégrée de l’imagerie hybride. Méd Nucl. 2010;34(8):490–511.
Strobel K, Burger C, Seifert B, Husarik DB, Soyka JD, Hany TF. Characterization of focal bone lesions in the axial skeleton: performance of planar bone scintigraphy compared with SPECT and SPECT fused with CT. AJR Am J Roentgenol. 2007;188(5):W467–74.
Zhang Y, Shi H, Li B, Xiu Y, Cai L, Gu Y, et al. Diagnostic value of 99mTc-MDP SPECT/spiral CT combined with three-phase bone scintigraphy in assessing suspected bone tumors in patients with no malignant history. Nucl Med Commun. 2015;36(7):686–94.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Section Editor information
Rights and permissions
Copyright information
© 2023 Springer Nature Switzerland AG
About this entry
Cite this entry
Van den Wyngaert, T. (2023). Tumors: Introduction. In: Van den Wyngaert, T., Gnanasegaran, G., Strobel, K. (eds) Clinical Atlas of Bone SPECT/CT. Springer, Cham. https://doi.org/10.1007/978-3-031-26449-8_109
Download citation
DOI: https://doi.org/10.1007/978-3-031-26449-8_109
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-26448-1
Online ISBN: 978-3-031-26449-8
eBook Packages: MedicineReference Module Medicine