Abstract
The SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, and osteitis) is a rare inflammatory disorder of uncertain etiology. It is associated with the typical pattern of increased tracer uptake on bone SPECT/CT in the sternoclavicular joints, costosternal junction of the first ribs, and sternum. The CT part of the SPECT/CT study can be very useful to assess the typical anatomic changes in the bones of the anterior chest wall or the pelvic girdle.
This is a preview of subscription content, log in via an institution to check access.
References
Depasquale R, Kumar N, Lalam RK, Tins BJ, Tyrrell PN, Singh J, et al. SAPHO: what radiologists should know. Clin Radiol. 2012;67(3):195–206.
Gupta N, Verma R, Belho ES. Bone scan and SPECT/CT scan in SAPHO syndrome. Indian J Nucl Med. 2019;34(4):349–50.
Liu S, Tang M, Cao Y, Li C. Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome: review and update. Ther Adv Musculoskelet Dis. 2020;12:1759720X20912865.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Section Editor information
Rights and permissions
Copyright information
© 2023 Springer Nature Switzerland AG
About this entry
Cite this entry
Van den Wyngaert, T. (2023). Inflammation and Infection: SAPHO Syndrome. In: Van den Wyngaert, T., Gnanasegaran, G., Strobel, K. (eds) Clinical Atlas of Bone SPECT/CT. Springer, Cham. https://doi.org/10.1007/978-3-031-26449-8_107
Download citation
DOI: https://doi.org/10.1007/978-3-031-26449-8_107
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-26448-1
Online ISBN: 978-3-031-26449-8
eBook Packages: MedicineReference Module Medicine