Abstract
Bryophytes are the largest group of non-vascular plants that occur in almost any land ecosystem and have remarkable impact on ecosystem functioning at a global level. Despite that they have evolved an extraordinary chemical diversity, only a few bryophytic species have been studied using metabolomic techniques. Ecometabolomics systematically investigates the composition of metabolic compounds in bryophytes and relates these to organismal and environmental interactions. The application of ecometabolomics to bryophytic organisms can lead to new insights into their molecular biology, can identify novel bioactive natural products, can shed light on the phylogenetic and evolutionary mechanisms bryophytes realize in order to sustain ecological change, or can greatly improve the mechanistic understanding of ecological processes that are mediated by metabolic compounds at various levels. In this chapter, we first describe ecometabolomics and provide an introduction to how it can be performed. We then focus on case studies covering the various research fields of natural product chemistry, chemodiversity, chemotaxonomy/chemophenetics, functional ecology and plant traits, bioindication and biomonitoring, bioactivities, and the molecular biology of bryophytes. Finally, we present the latest advancements in analytic and computational methods to show the tremendous potential of the emerging technology of ecometabolomics for research with bryophytic organisms.
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Abbreviations
- (C)CA:
-
(Canonical) Correspondence Analysis
- (N)MDS:
-
(Non-metric) Multi-Dimensional Scaling
- 4CL:
-
4-coumarate CoA ligase
- ACP:
-
Acyl carrier protein
- ANOVA:
-
Analysis of Variances
- C:
-
Net plant carbon
- C4H:
-
Cinnamate 4-hydrolase
- CAWG:
-
Chemical Analysis Working Group
- CBGA:
-
Cannabigerolic acid
- CHS:
-
Chalcone synthase
- CoA:
-
Coenzyme A
- DBR:
-
Double bond reductase
- DDA:
-
Data-dependent acquisition
- DIA:
-
Data-independent acquisition
- FAIR:
-
Findable, Accessible, Interoperable, Reusable
- FT-ICR-MS:
-
Fourier Transform Ion Cyclotron Resonance Mass-Spectrometry
- GC:
-
Gas chromatography
- GC/MS:
-
Gas chromatography coupled to mass-spectrometry
- H′:
-
Shannon diversity index
- IPP:
-
Isopentyl diphosphate delta isomerase
- J:
-
Pielou’s evenness
- LC:
-
Liquid chromatography
- LC/MS-MS:
-
liquid chromatography coupled with tandem mass-spectrometry
- m/z:
-
Mass-to-charge ratio
- MEP:
-
Non-mevalonate
- MS:
-
Mass-spectrometry
- MSI:
-
Metabolomics Standards Initiative
- MTPSL:
-
Microbial terpene synthase-like
- MVA:
-
Mevalonate
- N:
-
Nutrients
- NMR:
-
Nuclear magnetic resonance
- PAL:
-
Phenylalanine ammonia-lyase
- PCA:
-
Principal Component analyses
- PDH:
-
Pyruvate dehydrogenase
- PLS:
-
Partial Least Squares regression
- PLSDA:
-
PLS coupled with Discriminant Analysis
- QC:
-
Quality control
- RDA:
-
ReDundancy Analysis
- S:
-
Compound richness
- SOM:
-
Soil organic matter
- STCS:
-
Stilbene carboxylate synthase
- THC:
-
Tetrahydrocannabinol
- TIMS:
-
Ion-Mobility Mass-Spectrometry
- ToF:
-
Time of flight
- U:
-
Number of unique compounds
- VOCs:
-
Volatile organic compounds
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Acknowledgments
KP, YP, and HU acknowledge the support of iDiv (funded by the German Research Foundation, DFG-FZT 118, 202548816). KBJ was funded by NSERC via the CGS-MSFSS (Application No. 566822-2021). Further, we like to thank the Leibniz Foundation for supporting this study. Lastly, we like to thank Harald Zechmeister for providing valuable feedback and for improving the manuscript.
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Peters, K., Poeschl, Y., Blatt-Janmaat, K.L., Uthe, H. (2023). Ecometabolomics Studies of Bryophytes. In: Murthy, H.N. (eds) Bioactive Compounds in Bryophytes and Pteridophytes. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-031-23243-5_30
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Publisher Name: Springer, Cham
Print ISBN: 978-3-031-23242-8
Online ISBN: 978-3-031-23243-5
eBook Packages: Chemistry and Materials ScienceReference Module Physical and Materials ScienceReference Module Chemistry, Materials and Physics