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Germ Cell Tumors of the Ovaries

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  • First Online:
Handbook of Gynecology

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Abstract

The basic classification of ovarian germ cell tumors has largely remained unchanged for several decades. Ovarian germ cell tumors develop from primordial germ and stem cells that differentiate into extra-embryonal and somatic tissues. Most benign and malignant ovarian germ cell tumors can be accurately diagnosed due to their characteristic morphologic profiles. Several immunohistochemical (IHC) markers are widely available and can significantly facilitate tumor typing of germ cell tumors, especially in high-grade tumors or in atypical clinical scenarios. In this chapter, the clinicopathologic features of common ovarian germ cell tumors are reviewed.

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Authors and Affiliations

  1. Department of Pathology, Roswell Park Comprehensive Cancer Center, Administrative Services Buildings (ASB), Buffalo, NY, USA

    Mohamed Mokhtar Desouki

  2. Division of Anatomic Pathology, University of California San Diego Health System, La Jolla, CA, USA

    Oluwole Fadare

Authors
  1. Mohamed Mokhtar Desouki
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  2. Oluwole Fadare
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Corresponding author

Correspondence to Mohamed Mokhtar Desouki .

Editor information

Editors and Affiliations

  1. Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

    Donna Shoupe

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Desouki, M.M., Fadare, O. (2023). Germ Cell Tumors of the Ovaries. In: Shoupe, D. (eds) Handbook of Gynecology. Springer, Cham. https://doi.org/10.1007/978-3-031-14881-1_64

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  • DOI: https://doi.org/10.1007/978-3-031-14881-1_64

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-14880-4

  • Online ISBN: 978-3-031-14881-1

  • eBook Packages: MedicineReference Module Medicine

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