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Kidney Disorders

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Geriatric Medicine

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Abstract

Kidney disorders, whether in the form of renal insufficiency or electrolyte disturbances, are frequently encountered in the care of the geriatric population. Moreover, most older patients, especially over age 75 years, are more likely to die from a cardiovascular event than develop end-stage kidney disease (ESKD) even at severely reduced eGFR less than 30 mL/min/ 66 1.73 m2. In this chapter, we discuss the various disease states, both primary and systemic, that have an impact on kidney function in older adults. We begin by reviewing the natural course of the aging kidney, known as senescence, then transition to describe the key components of CKD care especially in older adults that includes the patient’s experience of illness which is influenced by the presence of comorbid conditions. Therefore, early identification and characterization of acute kidney injury and chronic kidney disease are important to limit the risk for overt kidney failure. Lastly, even in the face of normal or appropriate kidney function in this population, we review the disorders of electrolytes, such as potassium, sodium, and fluid, which are quite -common often related to prescription drugs and polypharmacy. To this end, we review the intersection between pharmacotherapeutics and the different causes of kidney injury, as well as appropriate drug dosing regimens.

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Author information

Authors and Affiliations

  1. Nephrology, UC Davis, Sacramento, CA, USA

    Jose Morfin

  2. UC Davis, Sacramento, CA, USA

    Tiana Jespersen Nizamic

Authors
  1. Jose Morfin
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  2. Tiana Jespersen Nizamic
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Correspondence to Jose Morfin .

Editor information

Editors and Affiliations

  1. California Association of Long Term Care Medicine, Newbury Park, CA, USA

    Michael R. Wasserman

  2. Betty Irene Moore School of Nursing, University of California, Davis, Sacramento, CA, USA

    Debra Bakerjian

  3. Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, USA

    Sunny Linnebur

  4. Division of Geriatrics, SUNY Upstate Medical University, Syracuse, NY, USA

    Sharon Brangman

  5. Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

    Matteo Cesari

  6. Section of Geriatric Medicine, Division of Internal Medicine, Department of Medicine, Cedars-Sinai, Beverly Hills, CA, USA

    Sonja Rosen

Section Editor information

  1. California Association of Long Term Care Medicine, Newbury Park, CA, USA

    Michael R. Wasserman M.D., CMD

  2. Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

    Matteo Cesari MD, PhD

  3. Geriatric Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

    Matteo Cesari MD, PhD

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Morfin, J., Jespersen Nizamic, T. (2024). Kidney Disorders. In: Wasserman, M.R., Bakerjian, D., Linnebur, S., Brangman, S., Cesari, M., Rosen, S. (eds) Geriatric Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-74720-6_56

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  • DOI: https://doi.org/10.1007/978-3-030-74720-6_56

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