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Sarcopenia

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Geriatric Medicine

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Abstract

During the last decade, sarcopenia has become one of the hottest topics in geriatrics. Sarcopenia is a major challenge in geriatrics due to its association with numerous negative health-related outcomes, such as falls, fractures, disability, loss of independence, need for long-term care placement, reduced quality of life, and death. The theoretical construct of sarcopenia as a generalized disorder of skeletal muscle tissue, which involves a reduction in muscle mass and muscle function, is widely accepted. Yet, its practical implementation is hampered by the existence of multiple and only partly overlapping operational definitions. As a result, sarcopenia remains very often underdiagnosed and, consequently, undertreated in daily practice. No drugs are currently recommended for the prevention or treatment of sarcopenia. On the other hand, evidence has accumulated on the efficacy of non-pharmacological treatments for the management of sarcopenia, above all physical exercise and nutritional interventions.

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Authors and Affiliations

  1. Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy

    Matteo Tosato, Anna Picca & Riccardo Calvani

  2. Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy

    Emanuele Marzetti

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  1. Matteo Tosato
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  2. Emanuele Marzetti
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  3. Anna Picca
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  4. Riccardo Calvani
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Correspondence to Emanuele Marzetti .

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Editors and Affiliations

  1. California Association of Long Term Care Medicine, Newbury Park, CA, USA

    Michael R. Wasserman

  2. Betty Irene Moore School of Nursing, University of California, Davis, Sacramento, CA, USA

    Debra Bakerjian

  3. Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, USA

    Sunny Linnebur

  4. Division of Geriatrics, SUNY Upstate Medical University, Syracuse, NY, USA

    Sharon Brangman

  5. Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

    Matteo Cesari

  6. Section of Geriatric Medicine, Division of Internal Medicine, Department of Medicine, Cedars-Sinai, Beverly Hills, CA, USA

    Sonja Rosen

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  1. Section of Geriatric Medicine, Division of Internal Medicine, Department of Medicine, Cedars-Sinai Medical Care Foundation, Beverly Hills, CA, USA

    Sonja Rosen MD

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Tosato, M., Marzetti, E., Picca, A., Calvani, R. (2024). Sarcopenia. In: Wasserman, M.R., Bakerjian, D., Linnebur, S., Brangman, S., Cesari, M., Rosen, S. (eds) Geriatric Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-74720-6_116

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