Abstract
Prader-Willi (PWS) syndrome is a genetically determined, complex, neurodevelopmental disorder characterized by a specific behavioral phenotype. The condition is best known as a syndromic cause of hyperphagia, resulting in early onset morbid obesity and consequent premature death, if the condition is not diagnosed early and managed properly. It is also characterized by a plethora of other developmental, cognitive, behavioral, and mental health challenges. The purpose of this chapter is to provide an overview of the changing behavioral phenotype of PWS across lifespan and discuss its distinctive features, current understanding, and available interventions.
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Abbreviations
- ADD:
-
Attention-deficit disorder
- ADHD:
-
Attention-deficit hyperactivity disorder
- ASD:
-
Autism spectrum disorder
- GH:
-
Growth hormone
- IQ :
-
Intelligence quotient
- mUPD:
-
Maternal uniparental disomy
- OCD:
-
Obsessive-compulsive disorder
- PWS:
-
Prader-Willi syndrome
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Krefft, M., Libura, M. (2022). Behavioral Phenotype of Patients with Prader-Willi Syndrome. In: Patel, V., Preedy, V. (eds) Eating Disorders. Springer, Cham. https://doi.org/10.1007/978-3-030-67929-3_77-1
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DOI: https://doi.org/10.1007/978-3-030-67929-3_77-1
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