Abstract
Psychiatric comorbidity indicates the possibility of diagnosing more than one disorder in the same individual. Anorexia nervosa presents a high psychiatric comorbidity with implications both on a theoretical and clinical level. Population-based and clinical-based studies provided lifetime and concurrent rate of the main psychiatric comorbidities in anorexia nervosa. In the community sample, anorexia nervosa presented a prevalence of approximately at least one psychiatric comorbidity ranging from 20% to 50%. In the clinical sample, results were oriented toward the search for the most frequent comorbid disorders. They are depressive and bipolar disorders, anxiety disorders, obsessive-compulsive disorders, psychosis, substance abuse disorder, and personality disorders. Concomitant psychiatric comorbidity has strong impact on the onset, course, clinical manifestations, prognosis, and treatment of AN; therefore, it should be carefully assessed and treated. Psychiatric comorbidity can impact on symptom severity, hinder functional recovery, substantially worsen outcome, and be a risk factor for mortality.
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Abbreviations
- ALSPAC:
-
Avon Longitudinal Study of Parents and Children
- AN:
-
Anorexia nervosa
- BD:
-
Bipolar disorder
- BED:
-
Binge eating disorder
- BN:
-
Bulimia nervosa
- BPD:
-
Borderline personality disorder
- CGAS:
-
Clinical global assessment scale
- CGI:
-
Clinical global improvement
- CI:
-
Confidence interval
- CRH:
-
Corticotropin-releasing hormone
- DSM:
-
Diagnostic and Statistical Manual of Mental Disorders (III, third edition; III R, third edition revised; IV, fourth edition; IV TR, fourth edition text revision; 5, fifth edition)
- EDs:
-
Eating disorders
- FFMI:
-
Fat free mass index
- FMI:
-
Fat mass index
- GAD:
-
Generalized anxiety disorder
- GWAS:
-
Genome-wide association study
- MDD:
-
Major depressive disorder
- NA:
-
Network analysis
- NCR-S:
-
National Comorbidity Replication Survey
- OCD:
-
Obsessive-compulsive disorder
- OR:
-
Odds ratio
- OSFED:
-
Other specific feeding and eating disorders
- SD:
-
Standard deviation
- SGA:
-
Second-generation antipsychotics
- SSRIs:
-
Selective serotonin reuptake inhibitors
- TCAs:
-
Tricyclic antidepressants
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Catone, G. (2022). Anorexia Nervosa and Concurrent Psychiatric Comorbidity. In: Patel, V., Preedy, V. (eds) Eating Disorders. Springer, Cham. https://doi.org/10.1007/978-3-030-67929-3_38-1
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DOI: https://doi.org/10.1007/978-3-030-67929-3_38-1
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