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POET and CLEAN-NET for Submucosal Tumor

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Gastrointestinal and Pancreatico-Biliary Diseases: Advanced Diagnostic and Therapeutic Endoscopy

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Abstract

With the advancement of technologies and operators’ skills, endoscopic treatment and surgery have been rapidly developing in recent years, giving rise to further minimally invasive procedures. The advent of the endoscopic submucosal dissection (ESD) technique made an evolution in the field of therapeutic endoscopy. This was followed by the development of per-oral endoscopic myotomy (POEM) procedure which finally succeeded in advancing the endoscopic treatment into the deeper submucosal or muscular layers, the “third space.” Surgery has also evolved its techniques. After the first development of laparoscopic surgery, most of the surgeries have been performed by laparoscopic surgeries instead of conventional open surgeries. In this decade, laparoscopic and endoscopic cooperative surgery (LECS) including combination of laparoscopic and endoscopic approaches for neoplasia with a non-exposure technique (CLEAN-NET), which is based on a concept of cooperative surgery while taking in the advantages of both endoscopic and laparoscopic techniques, has been developed and spread gradually. This current flow of therapeutic development is facilitating to fulfill the gap between old endoscopic treatment and conventional surgery, resulting in providing patients with optimal and minimally invasive treatments.

In this chapter, we discuss the management of submucosal tumors (SMTs) in the upper gastrointestinal (GI) tract, especially focusing on the procedures of per-oral endoscopic tumor resection (POET), one of the “third-space” endoscopic treatments, and CLEAN-NET, one of the LECS-related procedures. We hope this chapter gives you a deeper knowledge of the concepts and techniques of both endoscopic and laparoscopic surgery.

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Authors and Affiliations

  1. Digestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, Japan

    Manabu Onimaru & Haruhiro Inoue

Authors
  1. Manabu Onimaru
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  2. Haruhiro Inoue
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Editor information

Editors and Affiliations

  1. Division of Gastroenterology and Gastrointestinal Endoscopy IRCCS, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy

    Pier Alberto Testoni

  2. Digestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, Japan

    Haruhiro Inoue

  3. Department of Gastroenterology and Hepatology, Mayo Clinic Florida, Jacksonville, FL, USA

    Michael B. Wallace

Section Editor information

  1. Cancer Center, Mayo Clinic, Jacksonville, FL, USA

    Michael B. Wallace

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Onimaru, M., Inoue, H. (2022). POET and CLEAN-NET for Submucosal Tumor. In: Testoni, P.A., Inoue, H., Wallace, M.B. (eds) Gastrointestinal and Pancreatico-Biliary Diseases: Advanced Diagnostic and Therapeutic Endoscopy. Springer, Cham. https://doi.org/10.1007/978-3-030-56993-8_13

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  • DOI: https://doi.org/10.1007/978-3-030-56993-8_13

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-56992-1

  • Online ISBN: 978-3-030-56993-8

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