Synonyms
Cystadenoma; Cystosarcoma phyllodes
Clinical Features
Incidence
Fewer than two dozen cases have been reported.
Age
Patients aged 37–66 years.
Sex
Male.
Site
Seminal vesicles.
Treatment
See outcome.
Outcome
No recurrences of cystadenoma or fibroadenoma have been reported after excision. Adenosarcoma may be curable by cystoprostatectomy or may be incurable and metastatic (Fain et al. 1993; Laurila et al. 1992).
Macroscopy
These cystic to solid masses can be as large as 14 cm in size.
Microscopy
In cystadenoma, gland spaces of various sizes are lined by non-atypical cells, are arranged in a lobular pattern, and form branching lumens and cysts in a spindle cell stroma. Granular intraluminal secretions are usually noted. In fibroadenoma, the stromal component is more pronounced than in cystadenoma. Hypercellular stroma is composed of...
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References and Further Reading
Fain, J. S., Cosnow, I., King, B. F., Zincke, H., & Bostwick, D. G. (1993). Cystosarcoma phyllodes of the seminal vesicle. Cancer, 71(6), 2055–2061.
Laurila, P., Leivo, I., Mäkisalo, H., Ruutu, M., & Miettinen, M. (1992). Müllerian adenosarcomalike tumor of the seminal vesicle. A case report with immunohistochemical and ultrastructural observations. Archives of Pathology & Laboratory Medicine, 116(10), 1072–1076.
McKenney, J. K. (2018). Mesenchymal tumors of the prostate. Modern Pathology, 31(S1), S133–S142.
Paner, G. P., Lopez-Beltran, A., So, J. S., et al. (2016). Spectrum of cystic epithelial tumors of the prostate: Most cystadenocarcinomas are ductal type with intracystic papillary pattern. American Journal of Surgical Pathology, 40, 886–895.
Reikie, B. A., Yilmaz, A., Medlicott, S., et al. (2015). Mixed epithelial-stromal tumor (MEST) of seminal vesicle: A proposal for unified nomenclature. Advances in Anatomic Pathology, 22, 113–120.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this entry
Cite this entry
Cimadamore, A., Montironi, R. (2020). Seminal Vesicle Mixed Epithelial and Stromal Tumors. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4936
Download citation
DOI: https://doi.org/10.1007/978-3-030-41894-6_4936
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-41893-9
Online ISBN: 978-3-030-41894-6
eBook Packages: MedicineReference Module Medicine