Skip to main content

Stress Vulnerability Models

  • Reference work entry
  • First Online:
Encyclopedia of Behavioral Medicine

Synonyms

Stress diathesis models

Definition

Vulnerability models are used to identify factors that are causally related to symptom development. Stress vulnerability models describe the relation between stress and the development of (psycho)pathology. They propose an association between (1) latent endogenous vulnerability factors that interact with stress to increase the adverse impact of stressful conditions, (2) environmental factors that influence the onset and course of (psycho)pathology, and (3) protective factors that buffer against or mitigate the effects of stress on pathological responses.

Description

The prevalence of stress-related mental disorders encompassing mood and anxiety disorders in Europe is above 20%. This morbidity is associated with high health-care costs, disability, and potential mortality. It is widely acknowledged that there are individual differences in how stressful people judge a particular event to be as well as in their ability to cope with adverse...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 1,199.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 1,599.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References and Further Reading

  • Coan, J. A., & Allen, J. J. B. (2003). The state and trait nature of frontal EEG asymmetry in emotion. In K. Hugdahl & R. J. Davidson (Eds.), The asymmetrical brain (pp. 565–616). Cambridge, MA: The MIT Press.

    Google Scholar 

  • Curtis, W. J., & Cicchetti, D. (2003). Moving research on resilience into the 21st century: Theoretical and methodological considerations in examining the biological contributors to resilience. Development and Psychopathology, 15, 773–810.

    Article  PubMed  Google Scholar 

  • DeRijk, R. H., & de Kloet, E. R. (2008). Corticosteroid receptor polymorphisms: Determinants of vulnerability and resilience. European Journal of Pharmacology, 583, 303–311.

    Article  CAS  PubMed  Google Scholar 

  • Gotlib, I. H., Joormann, J., Minor, K. L., & Hallmayer, J. (2008). HPA axis reactivity: A mechanism underlying the associations among 5-HTTLPR, stress, and depression. Biological Psychiatry, 63, 847–851.

    Article  CAS  PubMed  Google Scholar 

  • Huizink, A., & De Rooij, S. (2018). Prenatal stress and models explaining risk for psychopathology revisited: Generic vulnerability and divergent pathways. Development and Psychopathology, 30(3), 1041–1062. https://doi.org/10.1017/S0954579418000354.

    Article  PubMed  Google Scholar 

  • Ingram, R. E., & Luxton, D. D. (2005). Vulnerability-stress models. In B. L. Hankin & J. R. Z. Abela (Eds.), Development of psychopathology: A vulnerability-stress perspective (pp. 32–46). Thousand Oaks: Sage.

    Chapter  Google Scholar 

  • Lupien, S. J., McEwen, B. S., Gunnar, M. R., & Heim, C. (2009). Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nature Reviews Neuroscience, 10, 434–445.

    Article  CAS  PubMed  Google Scholar 

  • Oitzl, M. S., Champagne, D. L., van der Veen, R., & de Kloet, E. R. (2010). Brain development under stress: Hypotheses of glucocorticoid actions revisited. Neuroscience and Biobehavioral Reviews, 34, 853–866.

    Article  CAS  PubMed  Google Scholar 

  • Stahl, S. M. (2008). Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications (3rd ed.). New York: Cambridge University Press.

    Google Scholar 

  • ter Heegde, F., De Rijk, R. H., & Vinkers, C. H. (2015). The brain mineralocorticoid receptor and stress resilience. Psychoneuroendocrinology, 52, 92–110.

    Article  PubMed  CAS  Google Scholar 

  • Van Praag, H. M., de Kloet, E. R., & van Os, J. (2004). Stress, the brain and depression. New York: Cambridge University Press.

    Book  Google Scholar 

  • Zubin, J., & Spring, B. (1977). Vulnerability-a new view of schizophrenia. Journal of Abnormal Psychology, 86, 103–126.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Conny W. E. M. Quaedflieg .

Editor information

Editors and Affiliations

Section Editor information

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Quaedflieg, C.W.E.M., Smeets, T. (2020). Stress Vulnerability Models. In: Gellman, M.D. (eds) Encyclopedia of Behavioral Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-39903-0_65

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-39903-0_65

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-39901-6

  • Online ISBN: 978-3-030-39903-0

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics