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Environmental Impact on Female Fertility and Pregnancy

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Environmental Endocrinology and Endocrine Disruptors

Part of the book series: Endocrinology ((ENDOCR))

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Abstract

Over the recent years, female fertility problems and number of pregnancies resulting into negative outcomes have been on the rise becoming a matter of particular concern among women of childbearing age. The rise in the above adverse reproductive health outcomes could be partly attributed to the exposure to hazardous factors ubiquitously found in the environment. To investigate this hypothesis, in this chapter, we summarize the current evidence on the impact of environmental factors and endocrine disruptors (EDs) on female fertility (either nonassisted or assisted) and on pregnancy outcomes (ectopic pregnancy, pregnancy losses, gestational diabetes, hypertensive disorders of pregnancy, preterm birth, intrauterine growth restriction, small and large for gestational age, and birth defects). Because it has been established that environmental factors and EDs are capable to induce epigenetic alterations, special care has been given to the exploration of their transgenerational effects on female fertility and pregnancy outcomes.

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Authors and Affiliations

  1. Department of Endocrinology and Metabolic Diseases, Larissa University Hospital, School of Medicine, University of Thessaly, Larissa, Greece

    Anastasia-Konstantina Sakali & Alexandra Bargiota

  2. 3rd Department of Pediatrics, Aristotle University of Thessaloniki, School of Medicine, “Hippokrateion” General Hospital of Thessaloniki, Thessaloniki, Greece

    Maria Papagianni

  3. Institute of Medical Physiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia

    Aleksandra Rasic-Markovic

  4. Unit of Endocrinology, Diabetes Mellitus and Metabolism, Aretaieion Hospital, Athens Medical School, National and Kapodistrian University of Athens, Athens, Greece

    George Mastorakos

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  1. Anastasia-Konstantina Sakali
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  2. Alexandra Bargiota
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  3. Maria Papagianni
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  4. Aleksandra Rasic-Markovic
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  5. George Mastorakos
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Editors and Affiliations

  1. Dipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Unità di Andrologia e Medicina della Riproduzione e della Sessualità Maschile e Femminile (FERTISEXCARES), Università Federico II di Napoli, Naples, Italy

    Rosario Pivonello

  2. Medical School, National and Kapodistrian University of Athens, Athens, Greece

    Evanthia Diamanti-Kandarakis

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Sakali, AK., Bargiota, A., Papagianni, M., Rasic-Markovic, A., Mastorakos, G. (2023). Environmental Impact on Female Fertility and Pregnancy. In: Pivonello, R., Diamanti-Kandarakis, E. (eds) Environmental Endocrinology and Endocrine Disruptors . Endocrinology. Springer, Cham. https://doi.org/10.1007/978-3-030-39044-0_6

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  • DOI: https://doi.org/10.1007/978-3-030-39044-0_6

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