Abstract
It is well established that a balanced diet plays a crucial role in maintaining the good health of the individual. Beyond this, a balanced diet also ensures the optimal intake of all macro- and micronutrients, which is vital to maintain a good skeletal homeostasis. Proper nutrition is indeed one of the factors which play a pivotal role in the regulation of bone remodeling, thereby playing a significant role in the prevention of metabolic skeletal diseases, like osteoporosis. This brief review will highlight the pivotal role of nutrition in supporting bone health.
References
Angus RM, Eisman JA. Osteoporosis: the role of calcium intake and supplementation. Med J Aust. 1988;148:630–3.
Cena H, Calder PC. Defining a healthy diet: evidence for the role of contemporary dietary patterns in health and disease. Nutrients. 2020;12:334.
Cooper C, Campion G, Melton LJ. Hip fractures in the elderly: a world-wide projection. Osteoporos Int. 1992;2:285–9.
Corrao G, Biffi A, Porcu G, et al. Executive summary: Italian guidelines for diagnosis, risk stratification, and care continuity of fragility fractures 2021. Front Endocrinol. 2023;14:1137671.
DeBoer MD, Lima AA, Oría RB, et al. Early childhood growth failure and the developmental origins of adult disease: do enteric infections and malnutrition increase risk for the metabolic syndrome? Nutr Rev. 2012;70:642–53.
Devlin MJ, Bouxsein ML. Influence of pre- and peri-natal nutrition on skeletal acquisition and maintenance. Bone. 2012;50:444–51.
Dyer J, Davison G, Marcora SM, et al. Effect of a Mediterranean type diet on inflammatory and cartilage degradation biomarkers in patients with osteoarthritis. J Nutr Health Aging. 2017;21:562–6.
Ettinger MP. Aging bone and osteoporosis: strategies for preventing fractures in the elderly. Arch Intern Med. 2003;163:2237.
García-Gavilán JF, Bulló M, Canudas S, et al. Extra virgin olive oil consumption reduces the risk of osteoporotic fractures in the PREDIMED trial. Clin Nutr. 2018;37:329–35.
Greco EA, Fornari R, Rossi F, et al. Is obesity protective for osteoporosis? Evaluation of bone mineral density in individuals with high body mass index. Int J Clin Pract. 2010;64:817–20.
Greco EA, Lenzi A, Migliaccio S. The pathophysiological basis of bone tissue alterations associated with eating disorders. Horm Mol Biol Clin Investig. 2016;28. Epub ahead of print. https://doi.org/10.1515/hmbci-2016-0006.
Grynpas MD, Pritzker KP, Hancock RG. Neutron activation analysis of bulk and selected trace elements in bones using a low flux SLOWPOKE reactor. Biol Trace Elem Res. 1987;13(1):333–44.
Günther ALB, Karaolis-Danckert N, Kroke A, et al. Dietary protein intake throughout childhood is associated with the timing of puberty. J Nutr. 2010;140:565–71.
Herzberg M, Foldes J, Steinberg R, et al. Zinc excretion in osteoporotic women. J Bone Miner Res. 1990;5:251–7.
Hoppe C, Mølgaard C, Juul A, et al. High intakes of skimmed milk, but not meat, increase serum IGF-I and IGFBP-3 in eight-year-old boys. Eur J Clin Nutr. 2004;58:1211–6.
Invernizzi M, de Sire A, D’Andrea F, et al. Effects of essential amino acid supplementation and rehabilitation on functioning in hip fracture patients: a pilot randomized controlled trial. Aging Clin Exp Res. 2019;31:1517–24.
Kimura T, Hino K, Kono T, et al. Maternal undernutrition during early pregnancy inhibits postnatal growth of the tibia in the female offspring of rats by alteration of chondrogenesis. Gen Comp Endocrinol. 2018;260:58–66.
Kontogianni MD, Melistas L, Yannakoulia M, et al. Association between dietary patterns and indices of bone mass in a sample of Mediterranean women. Nutrition. 2009;25:165–71.
Lifshitz F. Nutrition and growth – review. JCRPE. 2009;1:157. Epub ahead of print. https://doi.org/10.4274/jcrpe.v1i4.39.
Malmir H, Saneei P, Larijani B, et al. Adherence to Mediterranean diet in relation to bone mineral density and risk of fracture: a systematic review and meta-analysis of observational studies. Eur J Nutr. 2018;57:2147–60.
Manolagas SC. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis*. Endocr Rev. 2000;21:115–37.
Migliaccio S, Newbold RR, Bullock BC, et al. Alterations of maternal estrogen levels during gestation affect the skeleton of female offspring. Endocrinology. 1996;137:2118–25.
Moreno-Reyes R, Egrise D, Nève J, et al. Selenium deficiency-induced growth retardation is associated with an impaired bone metabolism and osteopenia. J Bone Miner Res. 2001;16:1556–63.
Mousavi SN, Koohdani F, Baghaban Eslaminejad M, et al. Extra virgin olive oil in maternal diet increases osteogenic genes expression, but high amounts have deleterious effects on bones in mice offspring at adolescence. Iran J Basic Med Sci. 2016;19. Epub ahead of print. https://doi.org/10.22038/ijbms.2016.7915.
Movassagh EZ, Vatanparast H. Current evidence on the association of dietary patterns and bone health: a scoping review. Adv Nutr. 2017;8:1–16.
Nakano M, Nakamura Y, Miyazaki A, et al. Zinc pharmacotherapy for elderly osteoporotic patients with zinc deficiency in a clinical setting. Nutrients. 2021;13:1814.
Noori M, Jayedi A, Khan TA, et al. Mediterranean dietary pattern and bone mineral density: a systematic review and dose-response meta-analysis of observational studies. Eur J Clin Nutr. 2022;76:1657–64.
Quattrini S, Pampaloni B, Gronchi G, et al. The Mediterranean diet in osteoporosis prevention: an insight in a peri- and post-menopausal population. Nutrients. 2021;13:531.
Rizzoli R. Dairy products and bone health. Aging Clin Exp Res. 2021;34:9–24.
Ros E. The PREDIMED study. Endocrinol Diabetes Nutr. 2017;64:63–6.
Rossi L, Migliaccio S, Corsi A, et al. Reduced growth and skeletal changes in ZincDeficient growing rats are due to impaired growth plate activity and inanition. J Nutr. 2001;131:1142–6.
Ruz M, Castillo-Duran C, Lara X, et al. A 14-mo zinc-supplementation trial in apparently healthy Chilean preschool children. Am J Clin Nutr. 1997;66:1406–13.
Sandstead HH, Prasad AS, Schulert AR, et al. Human zinc deficiency, endocrine manifestations and response to treatment. Am J Clin Nutr. 1967;20:422–42.
Savanelli MC, Barrea L, Macchia PE, et al. Preliminary results demonstrating the impact of Mediterranean diet on bone health. J Transl Med. 2017;15:81.
Soliman AT, Al Khalaf F, AlHemaidi N, et al. Linear growth in relation to the circulating concentrations of insulin-like growth factor I, parathyroid hormone, and 25hydroxy vitamin D in children with nutritional rickets before and after treatment: endocrine adaptation to vitamin D deficiency. Metabolism. 2008;57:95–102.
Tagliaferri C, Davicco M-J, Lebecque P, et al. Olive oil and vitamin D synergistically prevent bone loss in mice. PLoS One. 2014;9:e115817.
Wells JCK. The evolution of human adiposity and obesity: where did it all go wrong? Dis Model Mech. 2012;5:595–607.
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Migliaccio, S., Massari, M.C., Mocini, E. (2024). Nutrition and Bone Health. In: Brandi, M.L., Khan, A. (eds) Bone Metabolism, Parathyroid Glands, and Calciotropic Hormones. Endocrinology. Springer, Cham. https://doi.org/10.1007/978-3-030-19632-5_19-1
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DOI: https://doi.org/10.1007/978-3-030-19632-5_19-1
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