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Logopenic Variant Primary Progressive Aphasia

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Definition

This chapter provides an overview of logopenic variant progressive aphasia (lvPPA, also logopenic progressive aphasia or as logopenic PPA), which is a variant of primary progressive aphasia (PPA). This chapter reviews the major symptoms of lvPPA, as well as lvPPA epidemiology. The cognitive decline associated with lvPPA encompasses generalized language functions (e.g., word-finding difficulties, sentence repetition and comprehension deficits, single-word comprehension deficits), attention, memory recall, and visuo-spatial abilities, although phonology and syntax remain relatively intact. Anatomically, the progression of lvPPA is associated with atrophy in lateral/posterior temporal and medial parietal regions. This results in declining in memory, calculations skills, and repetition. Converging evidence indicates that lvPPA may be the most common aphasia phenotype of Alzheimer’s disease (AD). Currently, no curative treatments are effective in promoting communication function...

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Song, L. (2022). Logopenic Variant Primary Progressive Aphasia. In: Lester, J.N., O'Reilly, M. (eds) The Palgrave Encyclopedia of Critical Perspectives on Mental Health. Palgrave Macmillan, Cham. https://doi.org/10.1007/978-3-030-12852-4_99-1

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  • DOI: https://doi.org/10.1007/978-3-030-12852-4_99-1

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