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Forward Modeling and Tissue Conductivities

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Book cover Magnetoencephalography

Abstract

The neuroelectromagnetic forward model describes the prediction of measurements from known sources. It includes models for the sources and the sensors as well as an electromagnetic description of the head as a volume conductor, which are discussed in this chapter. First we give a general overview on the forward problem and discuss various simplifications and assumptions that lead to different analytical and numerical methods. Next, we introduce important analytical models which assume simple geometries of the head. Then we describe numerical models accounting for realistic geometries. The most important numerical methods for head modeling are the boundary element method (BEM) and the finite element method (FEM). The boundary element method describes the head by a small number of compartments, each with a homogeneous isotropic conductivity. In contrast, the finite element method discretizes the 3D distribution of the anisotropic conductivity tensor with the help of small-volume elements. Subsequently, we discuss in some detail how electrical conductivity information is measured and how it is used in forward modeling. Finally, we briefly introduce the lead field concept.

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Authors and Affiliations

  1. Institute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, Germany

    Jens Haueisen

  2. Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

    Thomas R. Knösche

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  1. Jens Haueisen
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  2. Thomas R. Knösche
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Correspondence to Jens Haueisen .

Editor information

Editors and Affiliations

  1. Faculty of Science, Department of Physics, University of Zagreb, Zagreb, Croatia

    Selma Supek

  2. Reno, NV, USA

    Cheryl J. Aine

Section Editor information

  1. Department of Radiology, MGH/HST Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, MA, USA

    Seppo P. Ahlfors

  2. Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA

    Seppo P. Ahlfors

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Haueisen, J., Knösche, T.R. (2019). Forward Modeling and Tissue Conductivities. In: Supek, S., Aine, C. (eds) Magnetoencephalography. Springer, Cham. https://doi.org/10.1007/978-3-030-00087-5_4

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