Chemical Structure
Acetazolamide (N-5-(sulfonyl)-1,3,4-thiadiazol-2-yl-acetamide) was first characterized as an anticonvulsant in the laboratory in 1952 (Bergstrom et al. 1952; Lederle 2001). Evidence of its antiseizure activity was initially described in 1956 (Lombroso et al. 1956; Merlis 1956). Chemically, acetazolamide is an unsubstituted sulphonamide (Fig. 259-1 ).
Chemical structure of acetazolamide (N-5-(sulfonyl)-1,3,4-thiadiazol-2-yl-acetamide)
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References
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Hovinga, C.A. (2010). Acetazolamide. In: Panayiotopoulos, C.P. (eds) Atlas of Epilepsies. Springer, London. https://doi.org/10.1007/978-1-84882-128-6_259
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