Basic research suggested that vitamin E, vitamin C, and other antioxidants reduce cardiovascular disease by trapping organic free radicals or deactivating excited oxygen molecules, or both, to prevent tissue damage (Packer 1991).
Antioxidants may slow atherosclerotic plaque formation by inhibiting LDL-C oxidation (Steinberg and Lewis 1997) modifying platelet activity (Steiner 1999; Mabile et al. 1999) and ameliorating endothelial dysfunction.
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