Definition
Hepatitis C virus (HCV) infection in HIV-infected patients is frequent since both viruses share common routes of transmission. HIV/HCV coinfection is associated with higher HCV viral loads and accelerated liver fibrosis progression particularly in those with low CD4 T cell counts, compared to HCV infection alone. While AIDS-related mortality dramatically decreased since the introduction of antiretroviral therapies (ART), there is an increasing impact of chronic viral hepatitis on hospital admissions and mortality among HIV-infected patients. Hepatic decompensations and HCCs are among the most common causes of death in HIV/HCV-coinfected patients. However, the recent major advances in HCV treatments have the potential to substantially reduce HCV-related morbidity and mortality among HIV-infected patients.
Hepatitis C in HIV-Infected Patients: A Frequent and Complex Coinfection
It is estimated that worldwide two to three million HIV-infected patients are coinfected with HCV...
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Rauch, A., Rockstroh, J.K. (2018). Hepatitis C Virus Infection and HIV. In: Hope, T.J., Richman, D.D., Stevenson, M. (eds) Encyclopedia of AIDS. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-7101-5_426
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DOI: https://doi.org/10.1007/978-1-4939-7101-5_426
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