Quantification of Regulation in Networks with Positive and Negative Interaction Weights

Years and Authors of Summarized Original Work

• 2011; Campbell, Thakar, Albert

Problem Definition

A network representation of a complex system comprises nodes, which represent system elements, and edges, which represent interactions between the elements. Networks may be described in terms of their topology; for instance, some nodes may be connected to an atypically large number of other nodes, and some may act as bridge nodes that participate in paths between many other pairs of nodes (Fig. 1). For a review of topological network measures, see [1–3].

Quantification of Regulation in Networks with Positive and Negative Interaction Weights, Fig. 1

Common network measures applied to a sample 9-node network with symmetric interactions. Darker nodes have higher betweenness centrality (i.e., they tend to act as a bridge between other pairs of nodes); note that even nodes with low degree (i.e., few connections) may have high betweenness centrality. Highlighted edges show a shortest path (length...