Reference knowledge is the knowledge about a particular part of the world in a way that is independent from specific objectives, through a theory of the domain . Different knowledge bases reuse or extend subsets of the reference knowledge for application specific tasks.
Developing knowledge bases is a laborious process involving domain experts, knowledge engineers and computer scientists. To minimize this effort, often the core theory and concepts of a given domain are represented in a reference knowledgebase that are reused or extended by other application specific knowledge bases. Consider for example, in the biomedical domain, the Foundational Model of Anatomy  is considered a reference knowledge base for representing anatomy terms that can be used for representing the mouse anatomy.
One of the important advantages of using reference knowledge bases is that they provide interoperability  across the applications using the knowledge. The applications...
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