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Costs in Comparative Effectiveness Research

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Part of the book series: Health Services Research ((HEALTHSR))

Abstract

The chapter brings together discussions of quality in health care and comparative effectiveness research (CER). The backdrop to this chapter is the search for the highest quality of care in the health system. The specific question addressed is: can the goals of CER (i.e., evidence-informed decision-making to improve health-care quality) be achieved for all potential users of CER information (i.e., patients, clinicians, purchasers, and policy-makers) without information on costs? The finding is that CER can be undertaken effectively as a discrete activity without explicit consideration of costs. However, the broader goals of actors within the health-care system (i.e., “to improve health care at both the individual and population levels”) require information on CER as one input, but alone CER is insufficient. The goals for all groups of actors cannot be met without explicit consideration of costs. This is true for all potential users of CER information although the perspective of cost information required by each stakeholder group, not surprisingly, varies. Therefore, the contention is that CER, when coupled with information about cost, provides useful direction in creating high-quality care at the individual and population levels.

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References

  • American College of Physicians. Information on cost-effectiveness: an essential product of a national comparative effectiveness program. Ann Intern Med. 2008;148(12):956–61.

    Article  Google Scholar 

  • American Diabetes Association. Economic costs of diabetes in the U.S. in 2007. Diabetes Care. 2008;31(3):596–615.

    Article  Google Scholar 

  • Bell CM, Urbach DR, Ray JG, Bayoumi A, Rosen AB, Greenberg D, et al. Bias in published cost effectiveness studies: systematic review. BMJ. 2006;332(7543):699–703.

    Article  PubMed Central  PubMed  Google Scholar 

  • Bloche MG, Jacobson PD. The Supreme Court and bedside rationing. JAMA. 2000;284(21):2776–9.

    Article  CAS  PubMed  Google Scholar 

  • Brock DW. Ethical issues in the development of summary measures of population health status. In: Field MJ, Gold MR, Institute of Medicine, editors. Summarizing population health: directions for the development and application of population metrics. Washington, DC: National Academy Press; 1998. p. 73–91.

    Google Scholar 

  • Bryan S, Sofaer S, Siegelberg T, Gold M. Has the time come for cost-effectiveness analysis in US health care? Health Econ Policy Law. 2009;4(Pt 4):425–43.

    Article  PubMed  Google Scholar 

  • Carlsson LM, Peltonen M, Ahlin S, Anveden A, Bouchard C, Carlsson B, et al. Bariatric surgery and prevention of type 2 diabetes in Swedish obese subjects. N Engl J Med. 2012;367(8):695–704.

    Article  CAS  PubMed  Google Scholar 

  • Centers for Disease Control and Prevention. [Internet]. Atlanta: 2011 National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2011. [updated 2012 Jan 10; cited 2013 Sep 7]. Available from: http://www.cdc.gov/diabetes/pubs/factsheet11.htm

  • Chokshi DA, Farley TA. The cost-effectiveness of environmental approaches to disease prevention. N Engl J Med. 2012;367(4):295–7.

    Article  CAS  PubMed  Google Scholar 

  • Clement FM, Harris A, Li JJ, Yong K, Lee KM, Manns BJ. Using effectiveness and cost-effectiveness to make drug coverage decisions: a comparison of Britain, Australia, and Canada. JAMA. 2009;302(13):1437–43.

    Article  CAS  PubMed  Google Scholar 

  • Culyer AJ. Perspective and desire in comparative effectiveness research the relative unimportance of mere preferences, the central importance of context. Pharmacoeconomics. 2010;28(10):889–97.

    Article  PubMed  Google Scholar 

  • Daniels N. Just health care. Cambridge, MA: Cambridge University Press; 1985. 245 p.

    Book  Google Scholar 

  • Dixon JB, Zimmer P, Alberti RG, Rubino F. Bariatric surgery: an IDF statement for obese Type 2 diabetes. Diabet Med. 2011;28(6):628–42.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Docteur E, Berenson R. How will comparative effectiveness research affect the quality of health care? Timely analysis of immediate health policy issues. [Internet]. Feb 2010 [updated 2012 Jan 10; cited 2013 Sep 7]. Available from: http://www.urban.org/uploadedpdf/412040_comparative_effectiveness.pdf

  • Eddy DM. Clinical decision making: from theory to practice. Anatomy of a decision. JAMA. 1990;263(3):441–3.

    Article  CAS  PubMed  Google Scholar 

  • Eden J, Wheatley B, McNeil B, Sox H, editors. Knowing what works in health care: a roadmap for the nation. Washington, DC: National Academies Press; 2008. 256 p.

    Google Scholar 

  • Garber AM. Evidence-based coverage policy. Health Aff (Millwood). 2001;20(5):62–82.

    Article  CAS  Google Scholar 

  • Garber AM. A menu without prices. Ann Intern Med. 2008;148(12):964–6.

    Article  PubMed  Google Scholar 

  • Gold MR, Stevenson D, Fryback DG. HALYS and QALYS and DALYS, Oh My: similarities and differences in summary measures of population Health. Annu Rev Public Health. 2002;23:115–34.

    Article  PubMed  Google Scholar 

  • Hadorn DC. Setting health care priorities in Oregon: cost-effectiveness meets the rule of rescue. JAMA. 1991;265(17):2218–25.

    Article  CAS  PubMed  Google Scholar 

  • Harris J. QALYfying the value of life. J Med Ethics. 1987;13(3):117–23.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Harris J. Life: quality, value and justice. Health Policy. 1988;10(3):259–66.

    Article  CAS  PubMed  Google Scholar 

  • Institute of Medicine. Crossing the quality chasm: a new health system for the 21st century. Washington, DC: National Academy Press; 2001. 337 p.

    Google Scholar 

  • Institute of Medicine. For the public’s health: investing in a healthier future. Washington, DC: National Academy Press; 2012a. 296 p.

    Google Scholar 

  • Institute of Medicine. Accelerating progress in obesity prevention: solving the weight of the Nation. Washington, DC: National Academy Press; 2012b. 462 p.

    Google Scholar 

  • Jacobson PD, Kanna ML. Cost-effectiveness analysis in the courts: recent trends and future prospects. J Health Polit Policy Law. 2001;26(2):291–326.

    Article  CAS  PubMed  Google Scholar 

  • Koch T. Life quality vs the ‘quality of life’: assumptions underlying prospective quality of life instruments in health care planning. Soc Sci Med. 2000;51(3):419–27.

    Article  CAS  PubMed  Google Scholar 

  • Menzel P, Gold MR, Nord E, Pinto-Prades JL, Richardson J, Ubel P. Toward a broader view of values in cost-effectiveness analysis of health. Hastings Cent Rep. 1999;29(3):7–15.

    Article  CAS  PubMed  Google Scholar 

  • Miners AH, Garau M, Fidan D, Fischer AJ. Comparing estimates of cost effectiveness submitted to the National Institute for Clinical Excellence (NICE) by different organizations: retrospective study. BMJ. 2005;330(7482):65.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Mingrone G, Panunzi S, De Gaetano A, Guidone C, Iaconelli A, Leccesi L, et al. Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Engl J Med. 2012;366(17):1577–85.

    Article  CAS  PubMed  Google Scholar 

  • Mortimer D, Peacock S. Social welfare and the affordable care act: is it ever optimal to set aside comparative cost? Soc Sci Med. 2012;75(7):1156–62.

    Article  PubMed  Google Scholar 

  • Nord E, Pinto JL, Richardson J, Menzel P, Ubel P. Incorporating societal concerns for fairness in numerical valuations of health programmes. Health Econ. 1999;8(1):25–39.

    Article  CAS  PubMed  Google Scholar 

  • Rawles J. Castigating QALYs. J Med Ethics. 1989;15(3):143–7.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Russell LB, Gold MR, Siegel JE, Daniels N, Weinstein MC. The role of cost-effectiveness analysis in health and medicine. Panel on Cost-Effectiveness in Health and Medicine. JAMA. 1996;276(14):1172–7.

    Article  CAS  PubMed  Google Scholar 

  • Schauer PR, Kashyap SR, Wolski K, Brethauer SA, Kirwan JP, Pothier CE, et al. Bariatric surgery versus intensive medical therapy in obese patients with diabetes. N Engl J Med. 2012;366(17):1567–76.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Sox HC, Greenfield S. Comparative effectiveness research: a report from the Institute of Medicine. Ann Intern Med. 2009;151:203–5.

    Article  PubMed  Google Scholar 

  • Tunis SR. Why medicare has not established criteria for coverage decisions. N Engl J Med. 2004;350(21):2196–8.

    Article  CAS  PubMed  Google Scholar 

  • Wilensky GR. The policies and politics of creating a comparative clinical effectiveness research center. Health Aff (Millwood). 2009;28(4):w719–29.

    Article  Google Scholar 

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Correspondence to Stirling Bryan .

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Bryan, S., Gold, M. (2015). Costs in Comparative Effectiveness Research. In: Levy, A., Sobolev, B. (eds) Comparative Effectiveness Research in Health Services. Health Services Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7586-7_12-1

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  • DOI: https://doi.org/10.1007/978-1-4899-7586-7_12-1

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  • Publisher Name: Springer, Boston, MA

  • Online ISBN: 978-1-4899-7586-7

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