Encyclopedia of Metagenomics

2015 Edition
| Editors: Sarah K. Highlander, Francisco Rodriguez-Valera, Bryan A. White

Chronic Respiratory Disease, Asthma

Reference work entry
DOI: https://doi.org/10.1007/978-1-4899-7475-4_699

Synonyms

Lung microbiome in asthma; Microbiota in asthma

Definition

The types, distribution, and environmental interactions of airway-associated microbial populations in individuals with asthma.

Introduction

The purpose of this entry is to introduce and summarize current knowledge of the airway microbiome in asthma. The relationships between asthma and microbial exposures, colonization, or infection have been postulated and studied for decades (Huang and Lynch 2011; Huang 2013). Although acute respiratory infections can trigger exacerbations of asthma, chronic colonization or infection of the respiratory tract by specific organisms has also been linked to asthma (Martin et al. 2001; Johnston and Martin 2005; Bisgaard et al. 2007). Earlier studies, which have been reviewed recently (Huang and Lynch 2011), used primarily culture methods, serologic antibody assays, or targeted molecular tests to detect exposure to, or infection by, specific microbes. The focus of this entry is to present...

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References

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Pulmonary and Critical Care Medicine, School of MedicineUniversity of California San FranciscoSan FranciscoUSA