Encyclopedia of AIDS

Living Edition
| Editors: Thomas J. Hope, Douglas Richman, Mario Stevenson

HIV-2 Diagnosis and Viral Load Measurements

Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-9610-6_53-1

Definition

Detection and/or quantification of the presence of HIV-2 in biological materials, distinguishable from related lentiviruses, either directly as virus-specific nucleic acid or protein or indirectly as immunological responses to infection. Viral load measurements relate specifically to genome quantification and infection dynamics, usually within already diagnosed individuals.

Background

Human immunodeficiency virus type 2 (HIV-2), a member of the Retroviridae, represents a related but distinct group of infections to HIV-1, the global agent of acquired immunodeficiency syndrome (AIDS). While HIV-2 bears similarity to HIV-1, it represents a separate genetic, virologic, and epidemiologic entity of viruses with marked differences in natural history and disease associations (HIV Prevention in the Correctional System). Accurate, reliable diagnosis of HIV-2 infections is important not only from an individual perspective but when considering wider epidemiological and clinical...

Keywords

Europe Recombination Rubber Cote Cytidine 
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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Division of VirologyNational Institute for Biological Standards and ControlSouth MimmsUK