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Encyclopedia of AIDS pp 1–13Cite as

HIV-2 Diagnosis and Viral Load Measurements

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Definition

Detection and/or quantification of the presence of HIV-2 in biological materials, distinguishable from related lentiviruses, either directly as virus-specific nucleic acid or protein or indirectly as immunological responses to infection. Viral load measurements relate specifically to genome quantification and infection dynamics, usually within already diagnosed individuals.

Background

Human immunodeficiency virus type 2 (HIV-2), a member of the Retroviridae, represents a related but distinct group of infections to HIV-1, the global agent of acquired immunodeficiency syndrome (AIDS). While HIV-2 bears similarity to HIV-1, it represents a separate genetic, virologic, and epidemiologic entity of viruses with marked differences in natural history and disease associations (HIV Prevention in the Correctional System). Accurate, reliable diagnosis of HIV-2 infections is important not only from an individual perspective but when considering wider epidemiological and clinical...

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Author information

Authors and Affiliations

  1. Division of Virology, National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Hertfordshire, UK, EN6 3QG

    Neil J. Berry

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  1. Neil J. Berry
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Correspondence to Neil J. Berry .

Editor information

Editors and Affiliations

  1. Dept. Cell & Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA

    Thomas J. Hope

  2. Office of Graduate and Postdoctoral Studies, University of Miami, Miller School of Medicine, Miami, Florida, USA

    Mario Stevenson

  3. University of California, San Diego Dept. Pathology, La Jolla, California, USA

    Douglas Richman

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Berry, N.J. (2013). HIV-2 Diagnosis and Viral Load Measurements. In: Hope, T., Stevenson, M., Richman, D. (eds) Encyclopedia of AIDS. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9610-6_53-1

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  • DOI: https://doi.org/10.1007/978-1-4614-9610-6_53-1

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-9610-6

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