Antiretroviral Treatment in Resource-Limited Settings
Antiretroviral therapy (ART) treatment has been proven to slow the progression of disease and reduce the risk of transmission for individuals with human immunodeficiency virus (HIV) infection. The goal of ART treatment is to completely inhibit viral replication in vivo and sustain the effects for as long as possible.
Introduction on Impact
Access to ART in resource-limited settings (RLS) has provided opportunity for infected patients to achieve nearly normal life expectancy with clear health gains. Before 2001, many people in RLS did not have access to ART due to the high cost and lack of availability of antiretroviral drugs (ARVs). Under special terms in international trade law, manufacturers in RLS began to produce generic drugs in 2001. This production expanded ART coverage, and by 2012, 9.7 million individuals representing 61 % of all eligible HIV-infected patients under the 2010 World Health Organization (WHO) HIV treatment guidelines were on treatment in RLS. These...
KeywordsHepatitis Depression Tuberculosis Pancreatitis Anemia
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