Encyclopedia of AIDS

Living Edition
| Editors: Thomas J. Hope, Douglas Richman, Mario Stevenson

Antiretroviral Medications, Adult Care, and Treatment

Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-9610-6_166-1

Definition

Antiretroviral medication(s): There are currently five main groups of antiretroviral (ARV) medications used to treat HIV. They are called ARV medications because they act against the life cycle of the retrovirus HIV. The five groups are as follows (of note, they are categorized by how they interfere with the HIV life cycle with the sixth group/designation “multi-class combination products” containing different combinations of ARV medications from the main groups working against various components of the HIV life cycle):
  1. 1.

    Entry inhibitors: ARV medications in this class of ARVs effectively interfere with the receptor-mediated entry of the HIV virus into a cell. One subclass of entry inhibitors is the CCR5 antagonists; and the one medication approved for use currently in this subclass is maraviroc, with viroc standing for virus occupying. A new medication in this class, cenicriviroc, is currently in preclinical studies and may be available soon.

     
  2. 2.

    Fusion inhibitors: ARV...

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Copyright information

© Springer Science+Business Media LLC 2017

Authors and Affiliations

  1. 1.Vanderbilt Institute for Global Health (VIGH)Vanderbilt University School of MedicineNashvilleUSA

Section editors and affiliations

  • Sten Vermund
    • 1
  1. 1.Anna M.R. Lauder Professor of Public HealthYale School of Public HealthNew HavenUSA