Encyclopedia of AIDS

Living Edition
| Editors: Thomas J. Hope, Douglas Richman, Mario Stevenson

cART and Supportive Care for HIV-Associated Malignancies

Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-9610-6_15-1

Definition

cART is an abbreviation for combined antiretroviral therapy and generally refers to a three- or four-drug combination regimen of antiretroviral medications, which is considered standard treatment for human immunodeficiency virus-1 (HIV-1) infection. Another name for cART is highly active antiretroviral therapy (HAART). This treatment is important for suppressing HIV-1 replication and has greatly increased the longevity of individuals with this infection. As part of the treatment of malignancies in HIV-infected patients, cART and other supportive measures such as antiemetics, hematopoietic growth factors, blood transfusions, prophylactic and therapeutic antibiotics, antidiarrheal medications, and psychosocial support for each individual undergoing the stressful therapy for these often life-threatening cancers have greatly enhanced both the efficacy and tolerability of these treatments and allowed patients to achieve remissions and/or cure of their cancers.

cART as Treatment...

Keywords

Toxicity Lymphoma Transportation Neuropathy Sarcoma 
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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.UCLA Center for Clinical AIDS Research and Education (CARE Center)University of California, Los AngelesLos AngelesUSA